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Published on: September 12, 2017
Perinatal post mortem ultrasound (PMUS): a practical approach
Susan C Shelmerdine1,2, Neil J Sebire3,4, Owen J Arthurs3,4
1Great Ormond Street Hospital for Children NHS Foundation Trust, London, WC1N 3JH, UK. susan.shelmerdine@gosh.nhs.uk.
Postmortem perinatal ultrasound (PMUS) offers a non-invasive, accessible, and affordable alternative to traditional autopsy for investigating infant deaths. This method aids in differentiating normal postmortem changes from abnormalities, improving diagnostic accuracy.
Area of Science:
- Medical Imaging
- Pediatric Pathology
- Ultrasound Technology
Background:
- Declining consent rates for perinatal autopsies necessitate alternative investigation methods.
- Postmortem imaging, particularly ultrasound, is gaining traction as a non-invasive approach.
- Existing research primarily focuses on CT and MRI, with limited guidance on ultrasound.
Purpose of the Study:
- To highlight the utility of perinatal postmortem ultrasound (PMUS) as a non-invasive autopsy alternative.
- To provide guidance on PMUS techniques, preparation, and interpretation.
- To discuss common findings and differentiate normal postmortem changes from pathology.
Main Methods:
- Focus on ultrasound imaging techniques for perinatal deaths.
- Exploration of practical considerations for conducting PMUS.
- Review of case examples to illustrate diagnostic capabilities.
Main Results:
- Postmortem ultrasound demonstrates reasonable diagnostic accuracy for perinatal deaths.
- PMUS is more accessible and affordable than CT or MRI.
- Guidance on image acquisition and interpretation is currently limited.
Conclusions:
- Perinatal postmortem ultrasound is a valuable non-invasive tool for investigating infant mortality.
- Standardized protocols and further research are needed to optimize PMUS application.
- PMUS can supplement or replace traditional autopsy in specific scenarios.
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