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Basophil Activation Test for Allergy Diagnosis
Published on: May 31, 2021
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Management of ocular allergy
Andrea Leonardi1, Diana Silva2, Daniel Perez Formigo3,4
1Ophthalmology Unit, Department of Neuroscience, University of Padua, Padua, Italy.
Allergy
|March 20, 2019
Summary
Effective treatments exist for ocular allergy (OA), but optimal management for severe or perennial forms is lacking. Current recommendations focus on topical medications and immunotherapy for persistent cases.
Area of Science:
- Ophthalmology
- Allergy and Immunology
- Pharmacology
Background:
- Ocular allergy (OA) management is a significant concern across multiple medical specialties.
- Effective treatments are available, yet optimal strategies for severe and perennial OA remain elusive.
Purpose of the Study:
- To systematically review current treatments and management strategies for ocular allergy.
- To propose evidence-based recommendations for OA management.
Main Methods:
- Systematic literature review of publications in MEDLINE, Scopus, and Web Science.
- Inclusion of systematic reviews and meta-analyses addressing OA treatments.
- Extended literature search conducted if initial evidence was insufficient.
Main Results:
- Topical antihistamines, mast cell stabilizers, and dual-action drugs are first-line treatments, effectively reducing OA signs and symptoms.
- Safety and optimal dosing of topical corticosteroids remain a concern.
- Topical calcineurin inhibitors and allergen-specific immunotherapy are options for refractory or severe cases.
Conclusions:
- While effective treatments exist, challenges remain in managing severe and perennial ocular allergy.
- Recommendations for OA management have been developed based on current evidence and clinical experience.
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