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Related Experiment Video

Updated: Jan 27, 2026

The Establishment of a Murine Mandibular Molar Extraction Socket Healing Model
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Orthodontic extraction space closure with and without socket preservation: a comparative case analysis.

Edlira Zere, Shmuel Einy, Thabet Asbi

    Quintessence International (Berlin, Germany : 1985)
    |March 20, 2019
    PubMed
    Summary
    This summary is machine-generated.

    Socket preservation using hydroxyapatite β-tricalcium phosphate (HA-β-TCP) hindered orthodontic space closure. Natural healing allowed for better extraction space closure compared to grafted sites.

    Keywords:
    beta-tricalcium phosphatecalcium phosphateextractionorthodonticssocket preservationtooth movement

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    Area of Science:

    • Orthodontics
    • Periodontology
    • Biomaterials Science

    Background:

    • Preorthodontic socket preservation aims to improve ridge morphology for orthodontic tooth movement and space closure.
    • Grafting materials are used to enhance bone regeneration after tooth extraction.

    Purpose of the Study:

    • To compare orthodontic extraction space closure in a single patient using a split-mouth analysis.
    • To evaluate the effect of hydroxyapatite β-tricalcium phosphate (HA-β-TCP) grafting on orthodontic space closure.

    Main Methods:

    • A 13-year-old skeletal Class II patient underwent non-simultaneous extraction of mandibular first molars.
    • One extraction site healed naturally; the other was grafted with HA-β-TCP (4BONE BCH).
    • Orthodontic treatment was conducted over 3 years, comparing space closure between the sites.

    Main Results:

    • The naturally healed site achieved Class I occlusion.
    • The HA-β-TCP grafted site resulted in a 3-mm residual space and Class II occlusion.
    • The grafting material impeded orthodontic tooth movement and space closure.

    Conclusions:

    • HA-β-TCP grafting negatively impacted orthodontic extraction space closure.
    • Natural healing facilitated more effective space closure compared to HA-β-TCP grafting.
    • Grafting materials may act as an obstacle to orthodontic treatment goals.