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Updated: Jan 27, 2026

Ex Vivo Perfusion of the Rodent Placenta
Published on: May 30, 2019
Placenta Increta Presenting as Retained Placenta: A Report of 3 Cases
Stewart Cramer1, Fadi Hatem1, Debra S Heller2
1a Rochester General Hospital , University of Rochester School of Medicine , Rochester , NY , USA.
Objectives:
Morbid adherence is a risk factor for retained placenta (RP). We encountered three cases of placenta increta presenting clinically as delayed postpartum hemorrhage.
Methods:
This was a retrospective study of three cases of placenta increta presenting as RP.
Results:
One "routine" term placenta had heavy bleeding 2 weeks later; one missed abortion at 16 weeks with fetal and placental tissue submitted, had heavy bleeding 6 weeks later; and one elective abortion (no tissue submitted), had delayed postpartum bleeding leading to a curettage with blood only, then 6 weeks later a hysterectomy for menorrhagia. All 3 pathology specimens showed necrotic villi. However, all three also showed myometrium with keratin-positive interstitial trophoblasts in a zone of damaged myometrium, consistent with increta. All three cases had basal plate myofibers (BPMF) in the placenta, with BPMF recurrence in the two cases with another pregnancy.
Conclusion:
RP may be a presenting clinical manifestation of placenta increta.
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