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Updated: Jan 27, 2026
10:39
3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache
Published on: June 2, 2014
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New Daily Persistent Headache: a Diagnostic and Therapeutic Odyssey
Emily J Riddle1, Jonathan H Smith2
1Department of Neurology, Cincinnati Children's Hospital, Cincinnati, OH, USA.
Current Neurology and Neuroscience Reports
|March 20, 2019
Summary
New daily persistent headache (NDPH) is a rare disorder. Early identification and individualized treatment are key for managing this challenging condition.
Area of Science:
- Neurology
- Headache Medicine
Background:
- New daily persistent headache (NDPH) is a rare primary headache disorder.
- NDPH often presents with a refractory clinical course, making it difficult to manage.
Purpose of the Study:
- To review the development of NDPH.
- To outline diagnostic approaches for new daily headache.
- To explore management strategies and future therapies for NDPH.
Main Methods:
- Narrative review of existing literature.
- Analysis of case series and cohort studies.
Main Results:
- Identified novel triggering factors (e.g., Valsalva maneuvers) and subgroups with unique temporal profiles (e.g., thunderclap onset).
- Highlighted psychophysical profiles, such as increased pain catastrophizing.
- Explored potential treatment options, emphasizing individualized approaches.
Conclusions:
- Diagnosis and treatment of NDPH require a personalized approach based on clinical features.
- Earlier identification of patients, potentially predicting those with status migrainosus who will develop NDPH, may improve treatment efficacy.
Keywords:
Intractable headacheMigraineNew daily persistent headacheRefractory headacheStatus migrainosusMore Related Videos
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