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Obsessive-Compulsive Disorder01:28

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Obsessive-compulsive disorder (OCD) is a mental health condition characterized by recurrent obsessions, compulsions, or both, which consume significant time and interfere with daily functioning. Obsessions involve persistent, intrusive, and unwanted thoughts, images, or urges that evoke anxiety. Common examples include irrational fears of contamination or harm. Compulsions are repetitive behaviors or mental acts performed to reduce the anxiety caused by obsessions. For instance, individuals...
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Deep brain stimulation for obsessive-compulsive disorder.

Sruja Arya1, Megan M Filkowski1, Pranav Nanda2

  • 1Department of Neurosurgery, Baylor College of Medicine, Houston, Texas.

Bulletin of the Menninger Clinic
|March 20, 2019
PubMed
Summary
This summary is machine-generated.

Deep brain stimulation (DBS) offers a neurosurgical option for severe obsessive-compulsive disorder (OCD). This review covers DBS development for OCD, recent outcomes, and future research directions.

Keywords:
deep brain stimulationobsessive-compulsive disorderpsychiatric neurosurgery

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Area of Science:

  • Neurosurgery
  • Neurology
  • Psychiatry

Background:

  • Neurosurgical interventions have a long history in treating severe, refractory obsessive-compulsive disorder (OCD).
  • Deep brain stimulation (DBS) is a neurosurgical procedure commonly used for movement disorders.
  • DBS application for OCD evolved from earlier lesional procedures over the past two decades.

Purpose of the Study:

  • To review the development of deep brain stimulation (DBS) for obsessive-compulsive disorder (OCD).
  • To present the most recent outcome data for DBS in OCD treatment.
  • To identify areas for future research in DBS for OCD.

Main Methods:

  • Review of existing literature on DBS for OCD.
  • Analysis of outcome data from clinical studies.
  • Discussion of the historical progression from lesional procedures to DBS.

Main Results:

  • Deep brain stimulation (DBS) has shown promising results for OCD.
  • The therapy received Humanitarian Device Exemption (HDE) approval from the FDA in 2009.
  • The review synthesizes current knowledge on DBS efficacy and application in OCD.

Conclusions:

  • DBS is an established neurosurgical treatment for refractory OCD.
  • Continued research is essential to optimize DBS therapy for OCD patients.
  • Future research should focus on refining targets, programming, and patient selection for DBS in OCD.