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In Vitro Model of Human Cutaneous Hypertrophic Scarring using Macromolecular Crowding
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Collective Cell Migration: Wisdom of the Crowds Transforms a Negative Cue into a Positive One
1Department of Cell and Developmental Biology, University College London, Gower Street, London WC1E 6BT, UK.
Current Biology : CB
|March 20, 2019
Abstract:
The Semaphorin ligands and their Plexin receptors are known to induce cell-cell repulsion. A new study now finds that protrusion collapse, induced by Semaphorin-5C-Plexin-A interactions at the cell-cell contact, promotes planar polarization and collective migration of follicular cells in Drosophila.
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