[Prostate cancer reporting: needle biopsy and radical prostatectomy specimen]

Prostatic adenocarcinoma is the most common cancer affecting men. A substantial majority of patients have the diagnosis made on fine needle biopsies. Treatment choices ranging from surveillance to radical prostatectomy or radiation therapy are largely driven by the pathologic findings in the biopsy specimen. Our review focuses on important morphologic parameters in needle biopsy and radical prostatectomy specimens. This includes Gleason score, Gleason grade, tumor quantification as well as other parameters such as extraprostatic extension, seminal vesicle invasion, perineural invasion, lymphovascular invasion. Surgical margin status and lymph node status are also discussed. Our aim was to present the most recent international guidelines of reporting of prostate adenocarcinoma.