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A Simple Procedure to Assess Limit of Detection for Multisensor Systems
Ekaterina Oleneva1,2, Maria Khaydukova3,4, Julia Ashina5,6
1Institute of Chemistry, Saint-Petersburg State University, Universitetskaya emb., 7-9-11, 199304 Saint-Petersburg, Russia. ekaterina.oleneva@inbox.ru.
Sensors (Basel, Switzerland)
|March 21, 2019
Summary
This study introduces a straightforward method for determining the limit of detection (LOD) in multisensor systems. The new approach helps standardize multisensor analysis and aids in comparing it with other techniques.
Area of Science:
- Analytical Chemistry
- Sensor Technology
- Instrumental Analysis
Background:
- Multisensor systems lack standardized limit of detection (LOD) evaluation protocols.
- This deficiency complicates method comparison and hinders technological advancement.
- Existing methods for LOD determination are not universally applicable to multisensor arrays.
Purpose of the Study:
- To propose a simple and visually intuitive method for estimating the limit of detection (LOD) in multisensor systems.
- To establish a reliable procedure for LOD evaluation in multisensor analysis.
- To facilitate the comparison of multisensor techniques with other analytical methods.
Main Methods:
- The proposed approach assesses the evolution of mean relative error (MRE) values.
- MRE is evaluated across calibration series with increasing analyte concentrations.
- The limit of detection (LOD) is identified as the concentration where MRE values stabilize.
Main Results:
- The developed method provides a clear and comprehensible estimation of LOD.
- The approach was successfully validated using diverse real-world data from potentiometric multisensor systems.
- Stable MRE values indicate the concentration at which the sensor system reliably detects the analyte.
Conclusions:
- The proposed method offers a practical solution for LOD determination in multisensor studies.
- This technique enhances the comparability and reliability of multisensor analytical data.
- The findings support the further development and adoption of multisensor systems in analytical chemistry.
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