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Biomarkers in an Animal Model for Revealing Neural, Hematologic, and Behavioral Correlates of PTSD

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Combining Cognitive-Behavioral Conjoint Therapy for PTSD with 3,4-Methylenedioxymethamphetamine (MDMA): A Case

Anne C Wagner^1,2, Michael C Mithoefer³, Ann T Mithoefer³

¹a Department of Psychology , Ryerson University , Toronto , Canada.

Journal of Psychoactive Drugs

|March 21, 2019

Summary

Combining Cognitive Behavioral Conjoint Therapy for PTSD (CBCT) with MDMA-assisted therapy shows promise for reducing PTSD symptoms and improving relationship satisfaction in a case study.

Keywords:

CBT MDMA PTSD couples

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Area of Science:

Psychiatry
Psychology
Pharmacology

Background:

Posttraumatic stress disorder (PTSD) treatments have advanced, with cognitive behavioral therapies (CBT) improving outcomes for 50-60% of patients.
MDMA-assisted psychotherapy shows promise for PTSD treatment, but optimal therapeutic integration remains unclear.

Observation:

This case study details the integration of Cognitive Behavioral Conjoint Therapy for PTSD (CBCT) with MDMA in a pilot trial.
The participants were a couple with severe trauma histories, representing a demographic subset of the trial.

Findings:

The combined CBCT and MDMA approach was detailed, including methodology and participant experience.
This integrated treatment demonstrated reductions in PTSD symptoms and enhanced relationship satisfaction.

Implications:

Combining CBCT with MDMA may offer a novel therapeutic strategy for complex PTSD cases.
Further research into integrated therapeutic modalities could optimize PTSD treatment outcomes.