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Randomized controlled trial protocol to improve multisensory neural processing, language and motor outcomes in
Mary Lauren Neel1, Paul Yoder2, Pawel J Matusz3,4
1Nationwide Children's Hospital Division of Neonatology & Center for Perinatal Research, The Ohio State University, 5th floor; 575 Children's Crossroads, Columbus, OH, 43215, USA. marylauren.neel@nationwidechildrens.org.
BMC Pediatrics
|March 21, 2019
Summary
This study investigates a multisensory intervention for premature infants to improve sensory development. The intervention aims to enhance neurodevelopmental outcomes in high-risk infants, potentially improving long-term health.
Area of Science:
- Neonatal neuroscience
- Developmental pediatrics
- Sensory processing research
Background:
- Premature infants face risks to sensory development due to immature brains and NICU environments.
- Altered sensory development in preterm infants can negatively impact complex developmental processes.
- Current interventions do not specifically target sensory function rehabilitation during the neonatal period.
Purpose of the Study:
- To evaluate the efficacy of a novel multisensory intervention for preterm infants.
- To assess the impact of multisensory stimulation on brain-based measures of sensory processing.
- To determine if the intervention improves neurodevelopmental outcomes in former preterm infants.
Main Methods:
- A randomized controlled trial involving 200 preterm infants (32-36 weeks postmenstrual age).
- Intervention group received standard care plus multisensory stimulation (tactile, auditory, olfactory, vestibular).
- Primary outcome measured by time-locked EEG for multisensory processing; secondary outcomes assessed at 1-2 years corrected age.
Main Results:
- This section is not available in the provided abstract.
Conclusions:
- This is the first RCT using brain-based measures to assess a multisensory intervention's effect on preterm infant neurodevelopment.
- The protocolized intervention, therapist-administered and parent-supported, shows potential for wide NICU implementation.
- The findings may improve neurodevelopmental outcomes for premature infants through enhanced sensory processing.
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