Effect of thyrotropin-releasing hormone on vestibular compensation in primates

Continual administration of thyrotropin-releasing hormone (TRH) (250 micrograms/kg/day) for 14 days using an osmotic mini-pump in unilateral labyrinthectomized squirrel monkeys induced accelerated vestibular compensation. Decrease in total gait deviation counts and reduction of slow-phase eye velocity of spontaneous nystagmus were significantly faster in the TRH-treated group as compared with the control group.