Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Experimental Designs01:16

Experimental Designs

17.0K
An experimental design is a systematic process that allows researchers to evaluate the relationship between dependent and independent variables. There are three widely used types of experimental design - pre-experimental design, true experimental design, and quasi-experimental design. In pre-experimental design, the researcher compares the data before and after some interventions or treatments. The true-experimental design has more than one purposefully created group, a commonly measured...
17.0K
Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs01:20

Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs

245
Body:Bioequivalence experimental study designs are crucial methodologies used in evaluating and comparing the bioavailability of different drug products. These designs are categorized into various types: completely randomized, randomized block, repeated measures, cross and carry-over, and Latin square designs.Completely randomized designs involve randomly allocating treatments to all subjects participating in the experiment. This allocation is achieved by assigning unique random numbers to...
245
Gas Chromatography: Types of Columns and Stationary Phases01:17

Gas Chromatography: Types of Columns and Stationary Phases

2.3K
Gas chromatography (GC) relies on stationary phases to separate and analyze components in a sample. There are two main types of stationary phases: liquid and solid. Liquid stationary phases are non-volatile, thermally stable, and chemically inert liquids coated onto the column. Solid stationary phases are particles of adsorbent material, such as silica gel or molecular sieves.
For an analyte to remain on the column for a sufficient amount of time, it must exhibit some level of compatibility (or...
2.3K
Reliability and Validity01:29

Reliability and Validity

13.8K
Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
13.8K
Factorial Design02:01

Factorial Design

13.8K
Factorial Analysis is an experimental design that applies Analysis of Variance (ANOVA) statistical procedures to examine a change in a dependent variable due to more than one independent variable, also known as factors. Changes in worker productivity can be reasoned, for example, to be influenced by salary and other conditions, such as skill level. One way to test this hypothesis is by categorizing salary into three levels (low, moderate, and high) and skills sets into two levels (entry level...
13.8K
Group Design02:01

Group Design

10.4K
The most basic experimental design involves two groups: the experimental group and the control group. The two groups are designed to be the same except for one difference— experimental manipulation. The experimental group gets the experimental manipulation—that is, the treatment or variable being tested—and the control group does not. Since experimental manipulation is the only difference between the experimental and control groups, we can be sure that any differences between...
10.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

In Situ Observation of Nonpolar to Strongly Polar Atom-Ion Collision Dynamics.

Physical review letters·2024
Same author

Coherent Control of the Fine-Structure Qubit in a Single Alkaline-Earth Atom.

Physical review letters·2024
Same author

ψ(2S) Suppression in Pb-Pb Collisions at the LHC.

Physical review letters·2024
Same author

Measurements of Groomed-Jet Substructure of Charm Jets Tagged by D^{0} Mesons in Proton-Proton Collisions at sqrt[s]=13  TeV.

Physical review letters·2023
Same author

Measurement of the Lifetime and Λ Separation Energy of _{Λ}^{3}H.

Physical review letters·2023
Same author

Randomized phase-III study of low-dose cytarabine and etoposide + /- all-trans retinoic acid in older unfit patients with NPM1-mutated acute myeloid leukemia.

Scientific reports·2023

Related Experiment Video

Updated: Jan 27, 2026

Laser Micromachining for Polymer Surface Topography Design
05:49

Laser Micromachining for Polymer Surface Topography Design

Published on: September 19, 2025

469

Micromachined phase-shifted array-type Mirau interferometer for swept-source OCT imaging: design, microfabrication

C Gorecki1, J Lullin1, S Perrin1

  • 1FEMTO-ST Institute (UMR CNRS 6174, UBFC), 15B avenue des Montboucons, 25030 Besançon, France.

Biomedical Optics Express
|March 21, 2019
PubMed
Summary

We developed a compact and affordable optical coherence tomography (OCT) system using microelectromechanical systems (MEMS) technology. This innovation enables faster, non-invasive 3D imaging for early disease detection outside of hospital settings.

More Related Videos

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

3.8K
Design and Use of Multiplexed Chemostat Arrays
19:40

Design and Use of Multiplexed Chemostat Arrays

Published on: February 23, 2013

23.9K

Related Experiment Videos

Last Updated: Jan 27, 2026

Laser Micromachining for Polymer Surface Topography Design
05:49

Laser Micromachining for Polymer Surface Topography Design

Published on: September 19, 2025

469
Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

3.8K
Design and Use of Multiplexed Chemostat Arrays
19:40

Design and Use of Multiplexed Chemostat Arrays

Published on: February 23, 2013

23.9K

Area of Science:

  • Biomedical Engineering
  • Optical Imaging
  • Microfabrication

Background:

  • Optical Coherence Tomography (OCT) offers non-invasive 3D optical biopsies but is limited by bulky, expensive equipment, restricting its use in early diagnostics.
  • Micro-Opto-Electro-Mechanical Systems (MOEMS) technologies present a viable solution for reducing OCT system size and cost.

Purpose of the Study:

  • To design and fabricate a miniaturized OCT system using an active array of Mirau microinterferometers.
  • To implement phase-shifting techniques for enhanced sensitivity and elimination of interferometric artifacts.

Main Methods:

  • Design of a novel imaging system incorporating a 4x4 array of Mirau microinterferometers.
  • Microfabrication and assembly of the Mirau microinterferometer with vertical comb-drive microactuators for reference mirror control.
  • Integration with swept-source OCT for imaging.

Main Results:

  • Successful design and fabrication of a compact Mirau microinterferometer array.
  • Demonstration of phase-shifting capability for improved interferometric measurements.
  • Feasibility of swept-source OCT imaging with the developed MOEMS-based system.

Conclusions:

  • The proposed MOEMS-based Mirau microinterferometer array significantly reduces the size and cost of OCT systems.
  • This technology holds promise for widespread adoption of OCT as an accessible early diagnostic tool.