Related Experiment Video
Updated: Jan 27, 2026
10:50
Using In Vitro Fluorescence Resonance Energy Transfer to Study the Dynamics Of Protein Complexes at a Millisecond Time Scale
Published on: March 14, 2019
8.6K
Myelomeningocele: need for long-time complex follow-up-an observational study
Thomas Bakketun1, Nils Erik Gilhus1,2, Tiina Rekand2,3
11Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Scoliosis and Spinal Disorders
|March 21, 2019
Summary
Adults with myelomeningocele (MMC) require lifelong, multidisciplinary medical care and rehabilitation. This study highlights the significant need for continuous specialist follow-up to manage health complications and improve quality of life.
Area of Science:
- Neurology
- Neurosurgery
- Urology
- Gastroenterology
- Orthopedics
Background:
- Myelomeningocele (MMC) is a congenital condition with significant long-term health implications.
- Adult health issues in MMC patients are often under-documented in clinical settings.
- This study addresses the need for organized adult follow-up care for MMC.
Purpose of the Study:
- To determine the necessity of specialized medical follow-up for adults with MMC.
- To assess the need for structured, focused rehabilitation programs for adults with MMC.
Main Methods:
- Retrospective cohort study of adult MMC patients at a Norwegian university hospital.
- Analysis of specialized hospital consultations, including number and reasons.
- Correlation analysis between childhood health status, MMC level, age, and follow-up needs.
Main Results:
- 38 adult MMC patients had 672 consultations, primarily in neurology, neurosurgery, urology, gastroenterology, and orthopedics.
- Consultations were mostly planned, with pain and shunt failure as common reasons.
- Higher MMC complexity correlated with increased specialist consultations.
Conclusions:
- Continuous, lifelong, multispecialty follow-up and rehabilitation are essential for adults with MMC.
- Optimizing health services through systematic follow-up improves function, life satisfaction, and survival.
- Addressing the ongoing healthcare needs of adults with MMC is crucial.
Related Concept Videos
01:11Observational Studies
11.0K
Observational studies are a type of analytical study where researchers observe events without any interventions. In other words, the researcher does not influence the response variable or the experiment's outcome.
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
There are three types of observational studies – Prospective, retrospective, and cross-sectional.
Prospective Study
Prospective studies, also known as longitudinal or cohort studies, are carried out by collecting future data from groups sharing similar characteristics. One...
11.0K
02:30Naturalistic Observations
17.1K
If you want to understand how behavior occurs, one of the best ways to gain information is to simply observe the behavior in its natural context. However, people might change their behavior in unexpected ways if they know they are being observed. How do researchers obtain accurate information when people tend to hide their natural behavior? As an example, imagine that your professor asks everyone in your class to raise their hand if they always wash their hands after using the restroom. Chances...
17.1K
01:23Actor-Observer Effect
371
The actor-observer effect, a cognitive bias closely linked to the fundamental attribution error, refers to the tendency for individuals to attribute their behavior to external, situational factors while explaining others’ behavior in terms of internal, dispositional traits. This asymmetry in attribution significantly influences social perception and judgment.Cognitive Mechanisms Behind the EffectTwo primary psychological mechanisms contribute to the actor-observer effect: differences in...
371
01:12Observational Learning
888
Albert Bandura's observational learning, also known as imitation or modeling, occurs when a person observes and imitates another's behavior. It is a quicker process than operant conditioning. A well-known example is the Bobo doll study, where children who saw an adult acting aggressively towards the doll were more likely to act aggressively when left alone, compared to those who observed a nonaggressive adult. Many psychologists view observational learning as a form of latent learning...
888
02:41Protein Complex Assembly
16.7K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types. Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
Many viruses self-assemble into a fully functional unit using the infected host cell to...
16.7K
01:57Protein Complexes with Interchangeable Parts
2.9K
Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.9K