Related Experiment Video
Updated: Jul 9, 2026

Microbiota Analysis Using Two-step PCR and Next-generation 16S rRNA Gene Sequencing
Published on: October 15, 2019
The intestinal microbiome and Alzheimer's disease: A review
Zhuo Li1, Hua Zhu1, Ling Zhang1
1Institute of Medical Laboratory Animal Science Chinese Academy of Medical Sciences & Comparative Medical Center Peking Union Medical College Beijing China.
Abstract:
Alzheimer's disease (AD) is an increasingly common neurodegenerative disease. Since the intestinal microbiome is closely related to nervous system diseases, alterations in the composition of intestinal microbiota could potentially contribute to the pathophysiology of AD. However, how the initial interactions with intestinal microbes alter events later in life, such as during neurodegenerative diseases, is still unclear. This review summarizes what is known about the relationship between the intestinal microbiome and AD.
Related Concept Videos
Alzheimer's Disease: Overview
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ and tau...
Development of Human Microbiota
Dysbiosis of the Gut Microbiota
Gut-Brain Axis
Microbiota Modulation by Antibiotics
Alzheimer Disease ll: Pathophysiology

