Related Experiment Video
Updated: Jan 27, 2026
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Long-term Continuous EEG Monitoring in Small Rodent Models of Human Disease Using the Epoch Wireless Transmitter System
Published on: July 21, 2015
26.2K
Continuous EEG Monitoring in a Consecutive Patient Cohort with Sepsis and Delirium
Rikke M Nielsen1,2, Olalla Urdanibia-Centelles3, Esben Vedel-Larsen2
1Department of Neuroanesthesiology, The Neuroscience Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark.
Neurocritical Care
|March 21, 2019
Summary
Continuous electroencephalography (cEEG) can help identify delirium in sepsis patients. This study found distinct EEG patterns differentiate delirious from non-delirious septic individuals.
Area of Science:
- Neuroscience
- Critical Care Medicine
- Medical Diagnostics
Background:
- Delirium is a frequent yet underdiagnosed complication in sepsis patients.
- Early and accurate diagnosis of delirium is crucial for effective patient management in intensive care settings.
Purpose of the Study:
- To evaluate the utility of continuous electroencephalography (cEEG) in diagnosing delirium among patients with sepsis.
- To identify specific electroencephalographic markers associated with delirium in septic patients.
Main Methods:
- A prospective study involving 102 sepsis patients in a medical intensive care unit.
- Continuous EEG monitoring was initiated, with recordings analyzed alongside the Confusion Assessment Method for the ICU (CAM-ICU) delirium assessments.
- Correlation analysis was performed between EEG patterns and delirium status.
Main Results:
- 65% of patients experienced delirium during their ICU stay.
- Absence of delirium correlated with preserved high-frequency beta activity and EEG reactivity.
- Delirium was associated with increased low-frequency activity and reduced high-frequency activity on cEEG.
Conclusions:
- Continuous EEG monitoring shows promise as a tool to differentiate septic patients with delirium from those without.
- Specific EEG patterns, including high-frequency beta activity and reactivity, can serve as indicators in delirium assessment for sepsis patients.
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