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Protein Complex Assembly02:41

Protein Complex Assembly

16.7K
Proteins can form homomeric complexes with another unit of the same protein or heteromeric complexes with different types.  Most protein complexes self-assemble spontaneously via ordered pathways, while some proteins need assembly factors that guide their proper assembly. Despite the crowded intracellular environment, proteins usually interact with their correct partners and form functional complexes.
Many viruses self-assemble into a fully functional unit using the infected host cell to...
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Protein Complexes with Interchangeable Parts01:57

Protein Complexes with Interchangeable Parts

2.9K
Groups of proteins may form a complex where each protein in this complex has a different role in the overall execution of the complex’s function. Often some of the proteins in the complex can be replaced by a closely related variant to give a complex that contains many of the same components yet is functionally distinct.
The SCF ubiquitin ligase is a protein complex of five individual proteins. This complex attaches ubiquitin to other target proteins to mark them for degradation. In order...
2.9K
Formation of Complex Ions03:45

Formation of Complex Ions

26.0K
A type of Lewis acid-base chemistry involves the formation of a complex ion (or a coordination complex) comprising a central atom, typically a transition metal cation, surrounded by ions or molecules called ligands. These ligands can be neutral molecules like H2O or NH3, or ions such as CN− or OH−. Often, the ligands act as Lewis bases, donating a pair of electrons to the central atom. These types of Lewis acid-base reactions are examples of a broad subdiscipline called coordination...
26.0K
Complex Power01:14

Complex Power

901
Power engineers have introduced the concept of complex power to determine the cumulative effect of parallel loads. This idea plays a crucial role in power analysis because it encompasses all the details related to the power consumed by a specific load.
Complex power is defined as the multiplication of the voltage and the complex conjugate of the current. The magnitude of this power, known as apparent power, is measured in volt-amperes (VA). Notably, the angle of the complex power equates to the...
901
Complexation Equilibria: Factors Influencing Stability of Complexes01:09

Complexation Equilibria: Factors Influencing Stability of Complexes

836
In complexation reactions, metal cations are the electron pair acceptors, and the ligands are the electron pair donors. The stability of the metal complexes depends primarily on the complexing ability of the central metal ion and the nature of the ligands. Generally, the complexing ability of the metal ion depends on the size and charge of the ion. As the metal ion size increases, the stability of the metal complexes decreases, provided that the valency of the metal ion and the ligands remain...
836
Crystal Field Theory - Octahedral Complexes02:58

Crystal Field Theory - Octahedral Complexes

30.8K
Crystal Field Theory
To explain the observed behavior of transition metal complexes (such as colors), a model involving electrostatic interactions between the electrons from the ligands and the electrons in the unhybridized d orbitals of the central metal atom has been developed. This electrostatic model is crystal field theory (CFT). It helps to understand, interpret, and predict the colors, magnetic behavior, and some structures of coordination compounds of transition metals.
CFT focuses on...
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Related Experiment Video

Updated: Jan 27, 2026

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds
06:36

3D Printed Porous Cellulose Nanocomposite Hydrogel Scaffolds

Published on: April 24, 2019

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Cell Printing in Complex Hydrogel Scaffolds.

Benjamin E Noren, Rajib K Shaha, Alan T Stenquist

    IEEE Transactions on Nanobioscience
    |March 21, 2019
    PubMed
    Summary
    This summary is machine-generated.

    Researchers developed new microfabrication techniques for creating synthetic tissues. These advanced hydrogel microenvironments improve cell viability and allow for tunable mechanical properties in engineered tissues.

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    Area of Science:

    • Biomaterials Science
    • Tissue Engineering
    • Microfabrication

    Background:

    • Mimicking complex native tissue microarchitecture is crucial for functional synthetic constructs.
    • Existing microfabrication methods face challenges in achieving cellular-level precision and maintaining cell viability.

    Purpose of the Study:

    • To develop advanced polyethylene glycol diacrylate (PEGDA) hydrogel microenvironments for precise single-cell patterning.
    • To create composite scaffolds with tunable mechanical properties for tissue engineering applications.

    Main Methods:

    • Stereolithographic patterning of PEGDA hydrogels using a digital micromirror device to create microgels at decreasing length scales.
    • Assessment of cell viability in relation to feature size, with inert gas purging implemented to enhance survival.
    • Mechanical testing of composite PEGDA scaffolds to evaluate modulus adjustability.

    Main Results:

    • Successful creation of PEGDA microgels maintaining high cell viability at single-cell patterning scales.
    • Demonstrated dynamic adjustability of the modulus in composite PEGDA scaffolds.
    • Established a microfabrication approach for mimicking native tissue constructs at cellular and subcellular scales.

    Conclusions:

    • The developed microfabrication technique enables the creation of sophisticated synthetic tissue structures with improved cellular control.
    • This method advances the field of tissue engineering by providing tools to better recapitulate native tissue morphology and function.
    • The tunable composite scaffolds offer promising potential for various tissue engineering applications.