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Updated: Jan 27, 2026

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis
Published on: July 19, 2019
Lower urinary tract symptoms and sexual dysfunction in men with multiple sclerosis
André Luiz Farinhas Tomé1,2, Eduardo P Miranda3, José de Bessa Júnior3
1Divisao de Urologia, Faculdade de Medicina do ABC, Santo Andre, SP, BR.
Most men with multiple sclerosis (MS) experience lower urinary tract symptoms and sexual dysfunction. Increased neurological impairment significantly correlates with the severity of these conditions, impacting quality of life.
Area of Science:
- Neurology
- Urology
- Sexual Medicine
Background:
- Multiple sclerosis (MS) is a chronic neurological disease affecting young adults.
- Men with MS frequently report lower urinary tract symptoms (LUTS) and sexual dysfunction (SD).
- The interrelationship between LUTS, SD, and neurological impairment in MS requires further investigation.
Purpose of the Study:
- To determine the prevalence of LUTS and SD in men with MS.
- To examine the correlation between LUTS, SD, and the degree of neurological impairment.
Main Methods:
- A cross-sectional study involving 41 men with MS.
- Assessment of neurological impairment using the Expanded Disability Status Scale (EDSS).
- Evaluation of LUTS with the International Continence Society male short-form questionnaire and SD with the International Index of Erectile Function (IIEF).
Main Results:
- A high prevalence of SD (74.4%) was observed, defined by an IIEF score <45.
- Both voiding dysfunction and SD showed a significant increase with higher EDSS scores.
- A significant correlation was found between LUTS and SD (r=-0.31, p=0.04).
Conclusions:
- LUTS and SD are highly prevalent in male patients with MS.
- Neurological disease severity is a key predictor for the development of voiding and sexual dysfunctions in men with MS.
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