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Updated: Jan 27, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
What do Cochrane systematic reviews say about interventions for insomnia?
Florence de Lucca Melo1, Juan Fulgencio Welko Mendoza1, Carolina de Oliveira Cruz Latorraca2
1Undergraduate Medical Student, Escola Paulista de Medicina (EPM), Universidade Federal de São Paulo (UNIFESP), São Paulo (SP), Brazil.
Several interventions like acupuncture, music, and certain medications may benefit insomnia patients. However, more research is needed to confirm their effectiveness and safety for reliable clinical recommendations.
Area of Science:
- Sleep Medicine
- Evidence-Based Medicine
Background:
- Insomnia is a prevalent condition in the United States, leading to over five million physician visits annually.
- Effective treatment strategies for insomnia are crucial for public health.
Purpose of the Study:
- To systematically review Cochrane systematic reviews (SRs) evaluating interventions for insomnia treatment.
- To synthesize the findings, characteristics, and evidence certainty of included SRs.
Main Methods:
- Conducted a comprehensive search of the Cochrane Database of Systematic Reviews.
- Included seven SRs that assessed various insomnia interventions, including acupuncture, behavioral interventions, music, pharmacotherapy, phototherapy, and physical exercise.
Main Results:
- Seven SRs were analyzed, covering a range of interventions for insomnia.
- The certainty of evidence for these interventions varied from moderate to very low.
Conclusions:
- Acupuncture, music, physical exercise, and specific pharmacotherapies (paroxetine, doxepin, trimipramine, trazodone) show potential benefits for insomnia.
- Further high-quality studies are essential to confirm these benefits and harms, enabling definitive clinical practice recommendations.
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