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Robotic Ablation of Atrial Fibrillation
Published on: May 29, 2015
Procedural Outcomes of Patients With Heart Failure Undergoing Catheter Ablation of Atrial Fibrillation
Manju Bengaluru Jayanna1,2,3, Ala Mohsen1,2, Chakradhari Inampudi1
1Division of Cardiovascular Diseases, Section of Heart Failure and Transplant, University of Iowa Hospitals and Clinics, Iowa City, IA.
Insights
Catheter ablation for atrial fibrillation (AF) in heart failure (HF) patients shows similar recurrence rates after risk factor adjustment. However, HF predicts higher AF recurrence in paroxysmal AF cases.
Area of Science:
- Cardiology
- Electrophysiology
- Heart Failure Management
Background:
- Atrial fibrillation (AF) and heart failure (HF) often coexist due to shared risk factors.
- Catheter ablation is a common treatment for AF rhythm control.
Purpose of the Study:
- To identify characteristics and procedural outcomes of patients with HF undergoing AF catheter ablation.
- To compare AF recurrence rates between patients with and without HF post-ablation.
Main Methods:
- Retrospective cohort study of 264 AF patients undergoing catheter ablation.
- Analysis of 73 patients (28%) with known stage C HF (reduced or preserved ejection fraction).
- Comparison of procedural outcomes, focusing on AF recurrence rates at 3 months and 1 year.
Main Results:
- Patients with HF had higher unadjusted AF recurrence rates at 3 months and 1 year.
- After logistic regression adjusting for left atrial size, AF type, and CHA2DS2-VASc score, no significant difference in recurrence was observed.
- HF predicted higher recurrence in paroxysmal AF patients, with no difference between HF with reduced or preserved ejection fraction.
- Longer procedure length in HF patients, but no increased periprocedural complications.
Conclusions:
- While HF patients have more recurrence risk factors, adjusted AF recurrence rates post-ablation are similar to non-HF patients.
- Heart failure is a predictor of higher AF recurrence in the subset of patients with paroxysmal AF.
Background:
Catheter ablation is being increasingly performed for rhythm control of atrial fibrillation (AF). Heart failure (HF) frequently coexists with AF because they share common risk factors.
Study Question:
This study aims at identifying the characteristics and procedural outcomes of patients with HF undergoing catheter ablation of AF.
Study Design:
In this retrospective cohort study, we analyzed 264 consecutive patients who underwent catheter ablation for AF. Seventy-three patients (28%) had a known history of stage C HF either with reduced ejection fraction or preserved ejection fraction.
Measures And Outcomes:
We compared procedural outcomes between patients who had known HF with those who did not.
Results:
Patients with HF were more likely to have higher rates of atrial fibrillation recurrence at both 3 months (odds ratio 2.9, confidence interval = 1.5-5.7, P = 0.0022) and 1 year after the procedure (odds ratio 2.3, confidence interval 1.2-4.3, P = 0.0097) and risk factors for recurrence of AF including left atrial enlargement, persistent AF, and a higher CHA2DS2-VASc score. However, on logistic regression analysis adjusting for left atrial size, atrial fibrillation type (persistent vs. paroxysmal), and CHA2DS2-VASc score as covariates, there was no significant difference in AF recurrence rates at both 3 months and 1 year. Recurrence rates did not differ significantly between patients with HF either with reduced ejection fraction or preserved ejection fraction. Among patients with paroxysmal AF, HF was predictive of AF recurrence at both 3 months and 1 year after ablation. The procedure length was longer in patients with HF, but there were no differences in periprocedural complications.
Conclusion:
Patients with HF undergoing catheter ablation of AF tend to have more risk factors for recurrence, but after adjustment for risk factors, the recurrence rates were similar at 3 months and 1 year. Among patients with paroxysmal atrial fibrillation, HF was predictive of higher recurrence rates.
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