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In Vivo Functional Study of Disease-associated Rare Human Variants Using Drosophila
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No longer rare diseases and obstetric anesthesia
Current Opinion in Anaesthesiology
|March 21, 2019
Summary
Modern medical advances allow older and sicker women to become pregnant. This review highlights the unique challenges and considerations for managing these high-risk pregnancies to improve maternal and neonatal outcomes.
Area of Science:
- Obstetrics and Gynecology
- Anesthesiology
- Maternal-Fetal Medicine
Background:
- Maternal demographics are shifting due to medical advancements and lifestyle changes.
- An increasing number of older and medically complex women are pursuing pregnancy.
- High-risk parturient populations are becoming more prevalent in obstetric practice.
Purpose of the Study:
- To review and present the diverse high-risk parturient populations encountered in modern obstetric anesthesia.
- To inform obstetric anesthesiologists about the evolving landscape of high-risk pregnancies.
- To discuss the implications of changing maternal demographics on clinical practice.
Main Methods:
- Literature review of current trends in high-risk pregnancies.
- Synthesis of data on demographic shifts and associated medical conditions.
- Discussion of previously rare parturient populations now seen more frequently.
Main Results:
- Older women face increased pregnancy complications.
- Pregnant cancer survivors and those diagnosed during pregnancy are more common.
- Pre-existing neurological and cardiac conditions are increasingly managed during pregnancy.
- Rising obesity rates correlate with increased obstructive sleep apnea, posing maternal and neonatal risks.
- Increased use of opioids and marijuana presents challenges in managing substance use during pregnancy.
Conclusions:
- Further research is essential for understanding and managing these complex cases.
- Implementation of international guidelines is crucial for reducing maternal and neonatal morbidity.
- Proactive management strategies are needed for the evolving high-risk parturient population.
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