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Updated: Jan 27, 2026

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Isolation and Characterization of the Immune Cells from Micro-dissected Mouse Choroid Plexuses
Published on: February 3, 2022
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Bilateral Annular Isolated Choroidal Melanocytosis
Ophthalmic Surgery, Lasers & Imaging Retina
|March 21, 2019
Summary
This study describes a rare case of bilateral isolated choroidal melanocytosis in an annular pattern. This unique presentation of peripheral retinal hyperpigmentation requires further investigation for malignant potential.
Area of Science:
- Ophthalmology
- Medical Case Reports
- Pigmentary Disorders
Background:
- Choroidal melanocytosis is a rare condition characterized by increased melanin in the choroid.
- Isolated forms, particularly in an annular pattern, are exceptionally uncommon.
- Understanding the presentation and potential risks is crucial for patient management.
Observation:
- A 44-year-old woman presented with asymptomatic bilateral choroidal hyperpigmentation.
- The hyperpigmentation was observed in an annular pattern, spanning 12 clock hours of the peripheral retina.
- No other signs of uveal, scleral, or cutaneous melanocytosis were present.
Findings:
- Optical coherence tomography (OCT) revealed no choroidal thickening or subretinal fluid.
- The diagnosis of bilateral isolated choroidal melanocytosis was established based on clinical presentation.
- This specific annular pattern has not been previously documented in medical literature.
Implications:
- This case highlights a novel presentation of choroidal melanocytosis.
- Long-term follow-up is essential to ascertain the potential for malignant transformation.
- Further research into similar cases may refine diagnostic criteria and prognostic indicators.
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