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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction
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Postconditioning with Lactate-enriched Blood for Cardioprotection in ST-segment Elevation Myocardial Infarction

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Medium and long-term follow-up after ST-segment elevation myocardial infarction in a sub-Saharan Africa population: a

Hermann Yao1, Arnaud Ekou2, Aurore Hadéou2

  • 1Intensive Care Unit, Abidjan Heart Institute, 01 BPV 206 Abidjan, Abidjan, Côte d'Ivoire. hermannyao@gmail.com.

BMC Cardiovascular Disorders
|March 22, 2019
PubMed

Insights

ST-segment Elevation Myocardial Infarction (STEMI) patients in Abidjan had a 10.4% mortality rate, significantly higher in non-revascularized individuals. Age, female gender, and heart failure predicted death, highlighting the need for improved healthcare policies.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • ST-segment Elevation Myocardial Infarction (STEMI) poses a significant in-hospital mortality risk in Sub-Saharan Africa.
  • Limited data exists on the medium and long-term prognosis for STEMI patients in this region.
  • This study focuses on the outcomes of STEMI patients treated at the Abidjan Heart Institute.

Purpose of the Study:

  • To evaluate the medium and long-term prognosis of STEMI patients.
  • To compare mortality and cardiovascular complications between revascularized and non-revascularized STEMI patients.
  • To identify predictors of mortality after STEMI in the study population.

Main Methods:

  • A prospective cohort study was conducted with 260 STEMI patients from January 2012 to December 2015.
  • Patients were categorized into revascularized and non-revascularized groups for comparative analysis.
  • Kaplan-Meier survival analysis and multivariable Cox regression were employed to assess outcomes and identify mortality predictors.

Main Results:

  • The median follow-up period was 39 months, with 94 patients (36.1%) revascularized and 166 (63.8%) not.
  • Overall all-cause mortality was 10.4%, significantly higher in the non-revascularized group (p=0.04).
  • Age ≥ 70 years, female gender, and heart failure were identified as independent predictors of mortality.

Conclusions:

  • STEMI continues to be a major cause of mortality in the study setting.
  • Developing targeted healthcare policies is crucial to enhance patient care and improve long-term outcomes for STEMI survivors.
  • Revascularization strategies may play a role in improving survival rates for STEMI patients.
Abstract

Keywords:
MortalityST-segment elevation acute myocardial infarctionSub-Saharan Africa

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