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Updated: Jan 27, 2026

A Protocol for Housing Mice in an Enriched Environment
Published on: June 8, 2015
Enriched Environments as a Potential Treatment for Developmental Disorders: A Critical Assessment
Natalie J Ball1, Eduardo Mercado1, Itzel Orduña2
1Neural and Cognitive Plasticity Laboratory, Department of Psychology, University at Buffalo, The State University of New York, Buffalo, NY, United States.
Environmental enrichment benefits animals and may help children with neurodevelopmental disorders (NDDs). However, rigorous study design is needed to confirm its effectiveness in NDD interventions.
Area of Science:
- Neuroscience
- Developmental Psychology
- Animal Behavior
Background:
- Environmental enrichment (EE) in animals reduces stress and improves cognition.
- EE research is expanding to human therapeutic applications, particularly for neurodevelopmental disorders (NDDs).
- Existing research highlights potential benefits but also methodological challenges.
Purpose of the Study:
- To review the history of EE research.
- To examine EE as an intervention for NDDs in animal models and human children.
- To identify critical methodological considerations for evaluating EE efficacy in NDDs.
Main Methods:
- Literature review of EE studies in animal models and human children.
- Analysis of methodological factors in EE intervention research.
- Synthesis of findings to propose future research directions.
Main Results:
- EE has demonstrated positive effects on emotional reactivity, behavior, and cognition in animals.
- Preliminary evidence suggests potential benefits of EE for children with NDDs.
- Significant methodological limitations hinder definitive conclusions on EE efficacy for NDDs.
Conclusions:
- While promising, the therapeutic application of EE for NDDs requires further rigorous investigation.
- Standardization of EE protocols, robust control groups, and clear theoretical frameworks are essential.
- Future research must address these methodological gaps to accurately assess EE's impact on NDD trajectories.
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