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Antimicrobial resistance patterns in urinary E. coli isolates after a change in a single center's guidelines for
Patrick P Ryan1, Bryan C Knepper2, Rachel M Everhart3
1Department of General Internal Medicine,Denver Health and Hospital Authority,Denver,Colorado.
Infection Control and Hospital Epidemiology
|March 22, 2019
Abstract:
Recommending nitrofurantoin to treat uncomplicated cystitis was associated with increased nitrofurantoin use from 3.53 to 4.01 prescriptions per 1,000 outpatient visits, but nitrofurantoin resistance in E. coli isolates remained stable at 2%. Concomitant levofloxacin resistance was a significant risk for nitrofurantoin resistance in E. coli isolates (odds ratio [OR], 2.72; 95% confidence interval [CI], 1.04-7.17).