Related Experiment Video
Updated: Jan 27, 2026

Tissue-Engineered Graft for Circumferential Esophageal Reconstruction in Rats
Published on: February 10, 2020
Applied Bioengineering in Tissue Reconstruction, Replacement, and Regeneration
Juan M Colazo1,2, Brian C Evans3, Angel F Farinas4
11Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee.
Impact Statement:
The use of autologous tissue in the reconstruction of tissue defects has been the gold standard. However, current standards still face many limitations and complications. Improving patient outcomes and quality of life by addressing these barriers remain imperative. This article provides historical perspective, covers the major limitations of current standards of care, and reviews recent advances and future prospects in applied bioengineering in the context of tissue reconstruction, replacement, and regeneration.
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