Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Switching of BJT01:22

Switching of BJT

841
Switching behavior in Bipolar Junction Transistors (BJTs) is a fundamental aspect utilized in various electronic circuits, particularly for digital logic applications like switches and amplifiers. In a typical switching circuit, a BJT alternates between cut-off and saturation modes, corresponding to the "off" and "on" states, respectively, thus behaving like an ideal switch.
Cut-off Mode ("Off" State): In this state, both the emitter-base and collector-base junctions are...
841
Introduction to Developmental Psychology01:27

Introduction to Developmental Psychology

1.5K
Developmental psychology explores the changes and continuities in human abilities throughout life, encompassing physical, cognitive, linguistic, and social dimensions. Human development is not restricted to growth, but includes aspects of decline, particularly in physical abilities as individuals age. Developmental psychologists seek to understand how people change as they age and how their mental and social skills evolve.Developmental MilestonesA key concept in developmental psychology is...
1.5K
Three Developmental Domains01:29

Three Developmental Domains

1.1K
Human development is typically examined across three main domains: physical, cognitive, and socio-emotional. These domains represent the significant areas of change and continuity throughout the lifespan, from infancy to late adulthood.
Physical Development
Physical processes, also known as maturation, encompass the biological changes that occur across an individual's life. These changes begin with genetic inheritance and continue through various stages, including growth in height and weight,...
1.1K
Fixed Action Patterns01:06

Fixed Action Patterns

17.6K
A fixed action pattern (FAP) is a specific, hard-wired sequence of behaviors that occurs in response to an external stimulus, called a sign stimulus. The behavior is “fixed” because it is essentially unchangeable—proceeding similarly across individuals of a species every time it occurs.
17.6K
Embryonic Stem Cells00:58

Embryonic Stem Cells

32.3K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
32.3K
Embryonic Stem Cells00:57

Embryonic Stem Cells

4.9K
Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
4.9K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Arthroscopic double row repair of massive posterosuperior tear: healing and functional outcomes.

JSES international·2026
Same author

Management of massive rotator cuff tears involving irreparable subscapularis tear by arthroscopically assisted latissimus dorsi transfer: clinical results.

Journal of shoulder and elbow surgery·2026
Same author

Outcomes after revision of anatomic total shoulder arthroplasty to reverse shoulder arthroplasty and comparison between cemented or metal-backed glenoid in platform systems.

European journal of orthopaedic surgery & traumatology : orthopedie traumatologie·2026
Same author

Sketching microprotein portraits.

Protein science : a publication of the Protein Society·2026
Same author

Chronic acromioclavicular dislocations repaired by modified Weaver-Dunn technique with two EndoButtons: retrospective review of twenty three cases.

International orthopaedics·2026
Same author

A morphological innovation, the fan of the water strider Rhagovelia, enables its conquest of turbulent streams.

The Journal of experimental biology·2026

Related Experiment Video

Updated: Jan 27, 2026

Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling
06:31

Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling

Published on: May 3, 2019

7.2K

The mlpt/Ubr3/Svb module comprises an ancient developmental switch for embryonic patterning.

Suparna Ray1, Miriam I Rosenberg2, Hélène Chanut-Delalande3

  • 1Department of Biology, Developmental Biology, University of Erlangen-Nuremberg, Erlangen, Germany.

Elife
|March 22, 2019
PubMed
Summary

Small open reading frames (smORFs) encoding micropeptides, like mille-pattes (mlpt), form an ancient developmental module. This module

Keywords:
D. melanogasterG. buenoiN. vitripennisO. fasciatusT. castaneumdevelopmentdevelopmental biologyembryogenesisevolutionevolutionary biologymicropeptide

More Related Videos

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo
11:13

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo

Published on: February 2, 2016

8.4K
Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains
06:18

Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains

Published on: November 30, 2021

5.0K

Related Experiment Videos

Last Updated: Jan 27, 2026

Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling
06:31

Surgical Size Reduction of Zebrafish for the Study of Embryonic Pattern Scaling

Published on: May 3, 2019

7.2K
Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo
11:13

Stem cell-like Xenopus Embryonic Explants to Study Early Neural Developmental Features In Vitro and In Vivo

Published on: February 2, 2016

8.4K
Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains
06:18

Optimized Bone Sampling Protocols for the Retrieval of Ancient DNA from Archaeological Remains

Published on: November 30, 2021

5.0K

Area of Science:

  • Developmental biology
  • Evolutionary developmental biology
  • Molecular genetics

Background:

  • Small open reading frames (smORFs) encode micropeptides with complex evolutionary histories.
  • Conserved peptides, including mille-pattes (mlpt), play roles in embryonic segmentation (Tribolium) and adult appendage development (Drosophila).

Purpose of the Study:

  • To investigate the evolutionary plasticity and conserved function of the Mlpt-Ubr3-Svb molecular complex.
  • To understand how changes in expression patterns contribute to the evolution of developmental processes.

Main Methods:

  • Comparative analysis of the Mlpt-Ubr3-Svb complex across insect species.
  • Genetic manipulation in Drosophila to alter Shavenbaby (Svb) expression timing.
  • Functional assays to assess the impact on embryonic segmentation and adult development.

Main Results:

  • The Mlpt-Ubr3-Svb complex represents an ancient module conserved for early insect embryo patterning.
  • Loss of segmentation function in Drosophila correlates with restricted Svb expression in early embryos.
  • Restoring early Svb expression in Drosophila induces segmentation defects dependent on mlpt function.

Conclusions:

  • The Mlpt-Ubr3-Svb complex demonstrates evolutionary plasticity, adapting to different developmental roles.
  • Changes in transcription factor expression timing can repurpose ancient developmental modules.
  • Conserved molecular complexes are constrained by essential genetic networks during evolution.