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Microneedle Array-Based Platforms for Future Theranostic Applications.

Olivia Howells1, Natasha Rajendran1, Sarah Mcintyre1

  • 1College of Engineering, Swansea University, Fabian Way, Crymlyn Burrows, Bay Campus, Swansea, SA1 8EN, UK.

Chembiochem : a European Journal of Chemical Biology
|March 22, 2019
PubMed
Summary
This summary is machine-generated.

Microneedle arrays offer future theranostic applications by combining drug delivery and diagnostics. This technology enables closed-loop systems for personalized disease management and precision medicine.

Keywords:
artificial pancreasmicroneedle arraystheranosticstransdermal delivery

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Pharmacology

Background:

  • Theranostics integrates disease biomarker identification, targeted drug delivery, and prognostic monitoring.
  • Microneedle array technology is established for drug delivery and continuous analyte monitoring in the skin.

Purpose of the Study:

  • To explore the potential of microneedle arrays for advanced theranostic applications.
  • To investigate the integration of microneedle-based drug delivery and diagnostics for closed-loop disease management.

Main Methods:

  • Review and conceptualization of microneedle array capabilities.
  • Discussion of integrating drug delivery and diagnostic functions within microneedle systems.
  • Exploration of closed-loop control strategies for theranostics.

Main Results:

  • Microneedle arrays can be leveraged for combined therapeutic and diagnostic functions.
  • Integration enables real-time monitoring and site-specific drug release.
  • Potential for developing closed-loop systems for personalized medicine.

Conclusions:

  • Microneedle arrays represent a promising platform for future theranostic applications.
  • This technology facilitates precision drug delivery and continuous disease monitoring.
  • Future development can lead to automated, closed-loop theranostic systems.