Co-encapsulation of imidacloprid and lambda-cyhalothrin using biocompatible nanocarriers: Characterization and...

Area of Science:

• Agricultural Science
• Nanotechnology
• Entomology

Background:

• Pesticide resistance management often involves insecticide mixtures.
• Conventional pesticide formulations present environmental challenges.
• Nanocarriers offer a promising approach for developing eco-friendly pesticide formulations.

Purpose of the Study:

• To co-encapsulate imidacloprid and lambda-cyhalothrin in liposomes for simultaneous delivery.
• To investigate the effect of chitosan coating on nanoliposome properties and insecticidal activity.
• To evaluate the environmental friendliness and efficacy of the nanoformulation against Myzus persicae.

Main Methods:

• Liposomes were formulated using ethanol injection and characterized by DLS, SEM, and FT-IR.
• Nanoliposomes were coated with varying concentrations of chitosan.
• Encapsulation efficiencies, particle size, and surface charge were determined.
• Residual insecticidal activity against Myzus persicae was assessed.

Main Results:

• High encapsulation efficiencies were achieved for lambda-cyhalothrin (93%) and imidacloprid (51%).
• Chitosan coating increased particle size to 69 nm and surface charge to +31 mV.
• Nanoformulations exhibited enhanced residual activity and duration compared to conventional mixtures.
• Insecticidal effects correlated with chitosan concentration in the formulation.

Conclusions:

• Co-encapsulation of imidacloprid and lambda-cyhalothrin in chitosan-coated liposomes is feasible.
• This nanoformulation provides a more environmentally friendly and effective alternative to conventional insecticide mixtures.
• The study highlights the potential of nanocarriers for sustainable pest management strategies.