Related Experiment Video
Updated: Jul 28, 2026

09:09
A Modified Heterotopic Swine Hind Limb Transplant Model for Translational Vascularized Composite Allotransplantation (VCA) Research
Published on: October 14, 2013
Computational Comparison Between a Classic Bifurcated Endograft and a Customized Model With "Dog Bone"-Shaped Limbs
Efstratios Georgakarakos1, Antonios Xenakis2, George S Georgiadis1
11 Department of Vascular Surgery, University Hospital of Alexandroupolis, Medical School, Democritus University of Thrace, Alexandroupolis, Greece.
Summary
The dog bone (DB) endograft design shows higher main body forces and iliac limb stresses compared to classic bifurcated stent-grafts. Further imaging follow-up is recommended to assess the DB design's long-term clinical performance.
Area of Science:
- Biomedical Engineering
- Medical Device Design
- Computational Fluid Dynamics
Background:
- Endovascular aneurysm repair (EVAR) is a common treatment for abdominal aortic aneurysms.
- Stent-graft design modifications aim to improve device performance and patient outcomes.
- The
- dog bone
- -shaped (DB) endograft is a novel design for challenging anatomies.
Purpose of the Study:
- To compare the hemodynamic characteristics of a classic bifurcated stent-graft with a DB endograft design.
- To analyze flow patterns, wall shear stress, and displacement forces using computational simulations.
Main Methods:
- 3D modeling and computational fluid dynamics (CFD) analysis were employed.
- Models simulated blood flow, comparing DB and classic bifurcated endografts of equal length.
- Key hemodynamic parameters quantified included time-averaged wall shear stress, oscillatory shear index (OSI), relative residence time (RRT), displacement forces, and maximum wall shear stress (WSS).
Main Results:
- The DB design exhibited higher displacement forces in the main body compared to the classic configuration.
- Maximum wall shear stress was highest at the iliac limbs for both designs, with the DB model showing higher peak values.
- The stenotic segments of the DB model displayed high stress but low OSI and very low RRT.
Conclusions:
- The DB endograft design is associated with increased displacement forces in the main body and elevated stresses in the iliac limbs.
- Regular imaging follow-up is crucial to evaluate the mid- and long-term clinical performance of the DB design.
Keywords:
aortic endograftbifurcationcomputational fluid dynamicscustom designdisplacement forceendovascular aneurysm repairhemodynamicsiliac limbsmain bodystent-graftwall shear stress
