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Updated: Jan 27, 2026

Isolation and Analysis of Aortic Arch and Root Lesions in an Atherosclerotic Mouse Model
Published on: February 14, 2025
Clinically-relevant morphometric parameters and anatomical variations of the aortic arch branching pattern
Basma Emad Aboulhoda1, Raed Khairy Ahmed2, Ahmed Sayed Awad3
1Department of Anatomy and Embryology, Faculty of Medicine, Cairo University, Giza, Egypt. doctor.basma@hotmail.com.
Insights
This study details aortic arch anatomy, finding 35% of patients have variations like the bovine arch. These morphometric data are crucial for planning endovascular interventions and device selection.
Area of Science:
- Anatomy
- Radiology
- Cardiovascular Interventions
Background:
- Advances in cardiac and endovascular interventions highlight the importance of aortic arch (AA) anatomy.
- Understanding anatomical variability and morphometric parameters of the AA and its branches is critical for procedural success.
Purpose of the Study:
- To delineate the morphometry and anatomical variations of the aortic arch branches.
- To illustrate correlations between morphometric data and anatomical variations.
Main Methods:
- Evaluation of coronal, axial, and sagittal CT multiplanar reformatted three-dimensional angiograms.
- Detailed analysis of morphometric parameters and branching patterns of the aortic arch.
Main Results:
- 35% of aortic arches exhibited abnormal branching patterns, including "bovine arch" (24%), common ostium variant (6%), and aberrant left vertebral artery (5%).
- Specific measurements for AA diameter, branch origins, outer diameters of branches (BCT, LCCA, LSA), and angles between vessels were recorded.
- Significant correlations were identified between morphometric data and anatomical variations.
Conclusions:
- The study provides essential anatomical variations and morphometric data for the aortic arch.
- This information is vital for patients undergoing aortic endovascular interventions.
- Data aids in selecting appropriate sizes, shapes, and types of angiographic catheters and devices.
Introduction:
The ever expanding advances in various domains of cardiac and endovascular interventions has drawn tremendous attention toward the importance of the anatomical variability and morphometric parameters of the aortic arch (AA) and its branches.
Methods:
The current study delineates the morphometry and anatomical variations of the AA branches by evaluating coronal, axial and sagittal CT multiplanar reformatted three-dimensional angiograms. Correlations between morphometric data as well as the distribution of morphometric data in relation to the anatomical variations were also illustrated.
Results:
35% of the examined AA showed abnormal branching patterns, the most common of which was the "bovine arch" (24%), followed by common ostium variant (6%) and aberrant left vertebral artery arising directly from AA (5%). The outer diameter of AA at its origin and its end was 33.83 and 22.06 mm, respectively. The distance between the origin of AA and the origin of brachiocephalic trunk (BCT), left common carotid artery (LCCA) and left subclavian artery (LSA) was 19.59, 23.01 and 26.01 mm, respectively. The outer diameter of BCT, LCCA and LSA was 15.7, 11.42 and 14.02 mm, respectively. The angles between the AA and the BCT, LCCA and LSA were 59.01°, 68.59° and 59.92°, respectively. The mean distance between the BCT and LCCA was 19.59 mm and the distance between the LCCA and the LSA was 23.01 mm. Significant positive and negative correlations between morphometric data as well as the distribution of morphometric parameters in relation to the anatomical variations have been identified.
Conclusion:
The illustrated anatomical variations and morphometric data provide cardinal information especially for patients undergoing aortic endovascular intervention, principally for choosing the size, shape and type of the angiographic catheters and devices to be delivered.
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