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Remote Monitoring of Patient-Reported Outcomes in Ulcerative Colitis: A Prospective Real-World Pilot Study.
Shaji Sebastian1, Jenna Roberts2, John Waller2
1IBD Unit, Hull and East Yorkshire Hospital NHS Trust, Hull, UK.
Pharmacoeconomics - Open
|March 23, 2019
Summary
Remote online reporting of patient-reported outcomes (PRO2) for ulcerative colitis (UC) symptoms was feasible. This method showed high patient adherence and could support frequent symptom assessment without increasing healthcare burden.
Area of Science:
- Gastroenterology and Hepatology
- Digital Health and Telemedicine
- Clinical Trial Methodology
Background:
- The 6-point Mayo score for ulcerative colitis (UC) utilizes two patient-reported outcomes (PRO2): stool frequency and rectal bleeding.
- Assessing the feasibility and acceptability of remote online PRO2 reporting is crucial for golimumab-treated UC patients.
Purpose of the Study:
- To evaluate the feasibility and acceptability of remote online PRO2 reporting in patients with ulcerative colitis (UC) receiving golimumab treatment.
- To assess patient adherence and satisfaction with a digital platform for symptom monitoring.
Main Methods:
- A UK-based, multi-centre, prospective, real-world, non-interventional pilot study.
- 52 UC patients completed PRO2 scores online every 4 weeks for 6 months.
- Anonymized data collection via an online platform, including demographics and a satisfaction questionnaire.
Main Results:
- High patient engagement: 90% completed baseline, with subsequent reporting success rates between 81-94% over 6 months.
- Diverse device usage: Patients utilized personal computers (44%), mobile phones (38%), and tablets (18%).
- Low attrition rates observed among patients initially willing to participate.
Conclusions:
- Remote online monitoring of PRO2 is feasible for UC patients treated with golimumab.
- The system demonstrated high patient adherence and could facilitate more frequent symptom assessments.
- This approach offers a potential solution to support symptom monitoring without overburdening healthcare resources.
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