Unilateral versus Bilateral Groin Puncture for Atrial Fibrillation Ablation: Multi-Center Prospective Randomized

Hee Tae Yu1, Dong Geum Shin2, Jaemin Shim3

  • 1Department of Cardiology, Yonsei University Health System, Seoul, Korea.

Yonsei Medical Journal
|March 23, 2019
PubMed

Insights

Unilateral groin puncture-single trans-septal ablation for atrial fibrillation (AF) significantly reduces post-procedure pain compared to the conventional bilateral approach. This method is safe and feasible for paroxysmal AF patients.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Minimally Invasive Procedures

Background:

  • Catheter ablation for atrial fibrillation (AF) necessitates heavy anticoagulation and can cause uncomfortable post-procedural hemostasis.
  • Conventional bilateral groin puncture-double trans-septal (BG-DT) ablation is a standard approach for AF treatment.

Purpose of the Study:

  • To compare patient satisfaction and safety between unilateral groin puncture-single trans-septal (UG-ST) ablation and conventional BG-DT ablation in paroxysmal AF patients.

Main Methods:

  • 222 patients with paroxysmal AF were randomized into UG-ST (n=148) and BG-DT (n=74) groups.
  • Patients in the UG-ST group were crossed over to BG-DT if pulmonary vein isolation was not achieved after three attempts.
  • Outcomes assessed included procedure time, major complications, pain scores, and AF recurrence.

Main Results:

  • No significant differences in procedure time or major complication rates were observed between the UG-ST and BG-DT groups.
  • The UG-ST group reported significantly lower access site pain, back pain, and total pain scores.
  • AF recurrence-free survival rates were similar between the two groups over a median follow-up of 20.2 months.

Conclusions:

  • Unilateral groin puncture-single trans-septal ablation is a feasible and safe alternative for paroxysmal AF treatment.
  • This approach significantly reduces post-procedural discomfort related to hemostasis compared to the conventional double trans-septal method.
Abstract

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