Related Experiment Video
Updated: Jan 27, 2026

Robotic Ablation of Atrial Fibrillation
Published on: May 29, 2015
Unilateral versus Bilateral Groin Puncture for Atrial Fibrillation Ablation: Multi-Center Prospective Randomized
Hee Tae Yu1, Dong Geum Shin2, Jaemin Shim3
1Department of Cardiology, Yonsei University Health System, Seoul, Korea.
Insights
Unilateral groin puncture-single trans-septal ablation for atrial fibrillation (AF) significantly reduces post-procedure pain compared to the conventional bilateral approach. This method is safe and feasible for paroxysmal AF patients.
Area of Science:
- Cardiology
- Electrophysiology
- Minimally Invasive Procedures
Background:
- Catheter ablation for atrial fibrillation (AF) necessitates heavy anticoagulation and can cause uncomfortable post-procedural hemostasis.
- Conventional bilateral groin puncture-double trans-septal (BG-DT) ablation is a standard approach for AF treatment.
Purpose of the Study:
- To compare patient satisfaction and safety between unilateral groin puncture-single trans-septal (UG-ST) ablation and conventional BG-DT ablation in paroxysmal AF patients.
Main Methods:
- 222 patients with paroxysmal AF were randomized into UG-ST (n=148) and BG-DT (n=74) groups.
- Patients in the UG-ST group were crossed over to BG-DT if pulmonary vein isolation was not achieved after three attempts.
- Outcomes assessed included procedure time, major complications, pain scores, and AF recurrence.
Main Results:
- No significant differences in procedure time or major complication rates were observed between the UG-ST and BG-DT groups.
- The UG-ST group reported significantly lower access site pain, back pain, and total pain scores.
- AF recurrence-free survival rates were similar between the two groups over a median follow-up of 20.2 months.
Conclusions:
- Unilateral groin puncture-single trans-septal ablation is a feasible and safe alternative for paroxysmal AF treatment.
- This approach significantly reduces post-procedural discomfort related to hemostasis compared to the conventional double trans-septal method.
Purpose:
Catheter ablation for atrial fibrillation (AF) requires heavy anticoagulation and uncomfortable post-procedural hemostasis. We compared patient satisfaction with and the safety of unilateral groin (UG) puncture-single trans-septal (ST) ablation with conventional bilateral groin (BG) puncture-double trans-septal (DT) ablation in paroxysmal AF patients.
Materials And Methods:
We enrolled 222 patients with paroxysmal AF (59.4±10.7 years old) who were randomized in a 2:1 manner into UG-ST ablation (n=148) and BG-DT ablation (n=74) groups. If circumferential pulmonary vein isolation could not be achieved after three attempts of touch-up ablation in the UG-ST group, the patient was crossed over to BG-DT by performing a left groin puncture.
Results:
Ten patients in the UG-ST group (6.8%) required crossover to the BG-DT approach. There were no significant differences in procedure time (p=0.144) and major complications rate (p>0.999) between the UG-ST and BG-DT groups. Access site pain (p=0.014), back pain (p=0.023), and total pain (p=0.015) scores were significantly lower for the UG-ST than BG-DT group as assessed by the Visual Analog Scale. Over 20.2±8.7 months of follow up, there was no difference in AF recurrence free-survival rates between the two groups (Log rank, p=0.984).
Conclusion:
UG-ST AF ablation is feasible and safe, and was found to significantly reduce post-procedural hemostasis-related discomfort, compared to the conventional DT approach, in patients with paroxysmal AF.
More Related Videos
08:00Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
Published on: June 15, 2015
06:25Cooling or Warming the Esophagus to Reduce Esophageal Injury During Left Atrial Ablation in the Treatment of Atrial Fibrillation
Published on: March 15, 2020
Related Concept Videos
Amyloid Fibrils
Amyloid deposits were observed as early as 1639 in the liver and the spleen. In 1854, Rudolph Virchow performed iodine staining,...
Amyloid Fibrils
Bioequivalence Experimental Study Designs: Completely Randomized and Randomized Block Designs
Lattice Centering and Coordination Number
Types of Unit Cells
Imagine taking a large number of identical...
Fibril-associated Collagen
For example, the type II collagen fibrils in cartilage have covalently bound type IX fibril-associated collagens at regular intervals. Other types of fibril-associated collagens are...
Center of Gravity