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Updated: Jan 27, 2026

Anticancer Efficacy of Photodynamic Therapy with Lung Cancer-Targeted Nanoparticles
Published on: December 1, 2016
Size-controlled synthesis of polymerized DNA nanoparticles for targeted anticancer drug delivery
Keonwook Nam1, Taehyung Kim, Young Min Kim
1Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 03722, Republic of Korea. yr36@yonsei.ac.kr.
Abstract:
We synthesized size-tunable polymerized DNA nanoparticles (PDNs) for cancer-targeted drug delivery via sequential processes of rolling circle amplification, condensation, and layer-by-layer assembly. The PDNs selectively delivered anti-sense oligonucleotides to target cancer cells and exhibited size-dependent gene regulation efficacy.
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