Recent Progress in Electrochemical pH-Sensing Materials and Configurations for Biomedical Applications

Area of Science:

• Electrochemistry
• Materials Science
• Biomedical Engineering

Background:

• pH-sensing materials and configurations are rapidly evolving, particularly for biomedical applications.
• Electrochemical pH sensors have seen significant advances, especially in biomedical fields.

Purpose of the Study:

• To review progress in electrochemical pH sensors from 2008-2018.
• To emphasize materials selection, system configurations, and testing protocols.
• To discuss the role of standards in advancing pH sensor technology.

Main Methods:

• Review of recent literature on electrochemical and optical pH sensors.
• Focus on electromechanical pH sensors and their biomedical applications.
• Summary of material chemistries (metal oxides, polymers) and geometrical features (thin films, quantum dots).

Main Results:

• Electrochemical pH sensors with optimized materials and geometries are suitable for biomedical applications.
• Development of necessary sensing standards and protocols is crucial for consistent benchmarking.
• Comparison of human body pH regulation with state-of-the-art sensors for biomedical suitability.

Conclusions:

• Challenges in electrochemical pH sensing need to be addressed.
• Integration of pH sensors with advanced electronics offers a platform for novel disease diagnostics and prevention technologies.
• Future research should focus on developing robust and reliable pH sensing systems for in vivo applications.