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Updated: Jan 27, 2026

Assessment of Neuromuscular Function Using Percutaneous Electrical Nerve Stimulation
Published on: September 13, 2015
Percutaneous Peripheral Nerve Stimulation to Control Postoperative Pain, Decrease Opioid Use, and Accelerate
Brian M Ilfeld1, Scott T Ball1, Steven P Cohen2
1University of California San Diego, 200 W Arbor Drive, San Diego, CA.
Percutaneous peripheral nerve stimulation (PNS) offers a non-opioid solution for orthopedic trauma pain. This therapy shows potential for reducing opioid use and improving function after surgery.
Area of Science:
- Orthopedics
- Pain Management
- Neuromodulation
Background:
- Orthopedic trauma presents a significant challenge in military healthcare, leading to disability and reduced readiness.
- Current pain management often involves opioids, contributing to prolonged use and potential complications.
- Effective non-opioid analgesia is crucial for recovery and functional restoration in Service members.
Purpose of the Study:
- To evaluate percutaneous peripheral nerve stimulation (PNS) as a non-opioid therapy for orthopedic trauma.
- To assess the potential of PNS for postoperative pain management, opioid cessation, and functional improvement.
- To summarize findings from case series investigating PNS in orthopedic pain contexts.
Main Methods:
- Review of case series data on percutaneous peripheral nerve stimulation (PNS).
- Analysis of PNS application in postoperative pain following total knee replacement (TKR).
- Evaluation of PNS for postamputation pain management.
Main Results:
- Percutaneous PNS demonstrated substantial pain relief in multiple case series.
- The therapy facilitated early cessation of opioid use postoperatively.
- Improved functional outcomes were observed in patients treated with PNS.
Conclusions:
- Percutaneous PNS shows significant potential as a non-opioid analgesic for orthopedic trauma.
- This neuromodulation technique may enhance recovery and reduce reliance on opioids.
- Further investigation into PNS for military orthopedic trauma is warranted.
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