Related Experiment Video

Updated: Jan 27, 2026

A Computational Method to Quantify Fly Circadian Activity
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Telling the Time with a Broken Clock: Quantifying Circadian Disruption in Animal Models

Laurence A Brown1, Angus S Fisk2, Carina A Pothecary3

  • 1Sleep and Circadian Neuroscience Institute (SCNi), Nuffield Department of Clinical Neurosciences, Oxford Molecular Pathology Institute, Sir William Dunn School of Pathology, South Parks Road, Oxford OX1 3RE, UK. laurence.brown@ndcn.ox.ac.uk.

Biology
|March 24, 2019
PubMed
Summary

Circadian rhythm disruption impacts health, affecting cognitive, metabolic, and immune functions. Consistent methods are needed to quantify this disruption, especially in lab rodents, for better health outcomes.

Keywords:
activity boutsdata analysisentrainmentfragmentationperiodogram

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