Related Experiment Video

Updated: Aug 16, 2026

Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro
11:37

Generation of Aggregates of Mouse Embryonic Stem Cells that Show Symmetry Breaking, Polarization and Emergent Collective Behaviour In Vitro

Published on: November 24, 2015

The role of cell adhesion in the synchronization and orientation of polarization in 8-cell mouse blastomeres

M H Johnson, B Maro, M Takeichi

    Journal of Embryology and Experimental Morphology
    |April 1, 1986
    PubMed

    More Related Videos

    Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets10:52

    Reconstitution of Basic Mitotic Spindles in Spherical Emulsion Droplets

    Published on: August 13, 2016

    In Vitro Reconstitution of Spatial Cell Contact Patterns with Isolated Caenorhabditis elegans Embryo Blastomeres and Adhesive Polystyrene Beads07:52

    In Vitro Reconstitution of Spatial Cell Contact Patterns with Isolated Caenorhabditis elegans Embryo Blastomeres and Adhesive Polystyrene Beads

    Published on: November 26, 2019

    Related Concept Videos

    Cleavage and Blastulation01:33

    Cleavage and Blastulation

    After a large-single-celled zygote is produced via fertilization, the process of cleavage occurs while zygotes travel through the uterine tube. Cleavage is a mitotic cell division that does not result in growth. With each round of successive cell division, daughter cells get increasingly smaller.
    Cell Migration01:09

    Cell Migration

    Cell migration, the process by which cells move from one location to another, is essential for the proper development and viability of organisms throughout their life. When cells are not able to migrate properly to their ordained locations, various disorders may occur. For example, disruption in cell migration causes chronic inflammatory diseases such as arthritis.
    Determining the Plane of Cell Division02:13

    Determining the Plane of Cell Division

    Positioning the cell division plane is a critical step during development and cell differentiation, particularly during mitosis when the plane is essential for determining the size of the two daughter cells. The cell division plane is perpendicular to the plane of chromosome segregation, but different types of organisms have different cell division mechanisms to suit their morphology and function. 
    Animal cells
    In animal cells, the cleavage furrow forms along the plane of cell division starting...
    Cell Motility through Blebbing01:16

    Cell Motility through Blebbing

    Blebs are a type of membrane protrusion formed by the internal hydrostatic pressure of the cytoplasm. Blebs are observed in several cell types, including fibroblasts, immune cells, and single-celled organisms like the amoeba. The primary function of blebs is cell locomotion and apoptosis, but they are also found during necrosis and cell division. The life cycle of a bleb comprises an initiation phase followed by the expansion and retraction phases.
    Blebbing Through the Matrix
    In multicellular...
    Cell Polarization by Rho Proteins01:21

    Cell Polarization by Rho Proteins

    Cell polarity is the asymmetric distribution of cellular and membrane components, making one side of the cell different from the other. This polarity is essential to many processes such as embryogenesis, axon migration, glucose transport across epithelial cells, and directional cell migration. A migrating cell responds to intracellular or extracellular signals via molecular cascades that reorganize the actin cytoskeleton to establish this polarity. In these cells, the Rho family proteins Cdc42,...
    Cytoskeletal Coordination in Cell Migration01:32

    Cytoskeletal Coordination in Cell Migration

    A migrating cell changes its shape during the cyclic events of attachment and detachment from the substratum and repositions the cell organelles correspondingly. These complex events are orchestrated by the dynamic cytoskeletal network comprising actin filaments, intermediate filaments, and microtubules. Cytoskeletal crosstalk — the direct and indirect communication between the different components — is crucial for this coordination. Direct communication involves various linker proteins that...