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Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.
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In redox reactions, the transfer of electrons occurs between reacting species. Electron transfer is described by a hypothetical number called the oxidation number (or oxidation state). It represents the effective charge of an atom or element, which is assigned using a set of rules.
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We have discussed why we form relationships, what attracts us to others, and different types of love. But what determines whether we are satisfied with and stay in a relationship? One theory that provides an explanation is social exchange theory. According to social exchange theory, we act as naïve economists in keeping a tally of the ratio of costs and benefits of forming and maintaining a relationship with others (Rusbult & Van Lange, 2003).
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Social Exchange Theory01:26

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As formulated by John Thibaut and Harold Kelley, Social Exchange Theory explains human relationships as economic-like exchanges that maximize rewards and minimize costs. This theory suggests that individuals engage in relationships to gain benefits and reduce burdens, similar to economic transactions. It has been widely applied to various types of relationships, including romantic, professional, and social interactions.Rewards and Costs in RelationshipsRelationship rewards include emotional...
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Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

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Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
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Capillary Exchange01:28

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The cardiovascular system's chief role is to disseminate gases, nutrients, waste, and other substances to the body's cells. Small molecules like gases, lipids, and lipid-soluble substances directly diffuse through capillary wall endothelial cell membranes. Glucose, amino acids, and ions, including sodium, potassium, calcium, and chloride, use transporters for facilitated diffusion via membrane-specific channels. Glucose, ions, and bigger molecules may also pass through intercellular...
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Related Experiment Video

Updated: Jan 27, 2026

Tuning Oxide Properties by Oxygen Vacancy Control During Growth and Annealing
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Tuning Oxide Properties by Oxygen Vacancy Control During Growth and Annealing

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Factors controlling surface oxygen exchange in oxides.

Yipeng Cao1, Milind J Gadre1, Anh T Ngo2

  • 1Department of Material Science and Engineering, University of Wisconsin-Madison, Madison, WI, 53706, USA.

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|March 24, 2019
PubMed
Summary

Lowering solid oxide fuel cell temperatures requires faster cathode kinetics. This study identifies surface diffusion as a bottleneck and proposes stabilizing cobalt oxide surfaces for improved oxygen reduction reaction rates.

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Area of Science:

  • Materials Science
  • Electrochemistry
  • Computational Chemistry

Background:

  • Solid oxide fuel cells (SOFCs) require efficient oxygen reduction reaction (ORR) at the cathode for commercial viability.
  • High operating temperatures are necessary due to slow oxygen exchange kinetics, hindering widespread adoption.
  • La0.5Sr0.5CoO3-δ (LSC) is a common perovskite cathode material.

Purpose of the Study:

  • To investigate the elementary reaction mechanisms of oxygen exchange on LSC cathode surfaces.
  • To identify the rate-limiting steps in the oxygen reduction reaction under operating conditions.
  • To propose strategies for enhancing ORR kinetics by controlling surface termination.

Main Methods:

  • Utilized ab initio computational methods to develop a quantitative elementary reaction model.
  • Simulated oxygen incorporation and dissociation on different LSC surface terminations.
  • Analyzed the influence of surface vacancy concentration on reaction pathways.

Main Results:

  • Identified lateral diffusion of oxygen adatoms and vacancies on the stable (001)-SrO surface as the rate-limiting step for oxygen incorporation.
  • Discovered that a high vacancy concentration on the metastable CoO2 termination significantly accelerates O2 dissociation (102-103 times faster).
  • Demonstrated that vacancy-assisted dissociation on CoO2 surfaces is much faster than on SrO surfaces.

Conclusions:

  • Surface termination plays a critical role in controlling oxygen exchange kinetics at SOFC cathodes.
  • Stabilizing the CoO2 termination with high vacancy concentrations can dramatically enhance ORR performance.
  • This finding offers a pathway to design more active cathode materials for lower-temperature SOFC operation.