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Naltrexone-associated Visual Hallucinations: A Case Report

Dae Bo Lee1, Young Sup Woo2, Won-Myong Bahk2

  • 1Department of Psychiatry, National Forensic Hospital.

Clinical Psychopharmacology and Neuroscience : the Official Scientific Journal of the Korean College of Neuropsychopharmacology
|March 26, 2019
PubMed

Insights

Naltrexone, an opioid receptor antagonist, may cause visual hallucinations in schizophrenia patients. Clinicians should monitor for this potential adverse effect when prescribing naltrexone for obesity.

Area of Science:

  • Neuroscience
  • Psychiatry
  • Pharmacology

Background:

  • Naltrexone is an opioid receptor antagonist studied for anti-obesity effects.
  • Its use in patients with severe mental illness, like schizophrenia, is being explored.
  • Adverse psychotic effects of naltrexone in schizophrenia patients remain under-investigated.

Purpose of the Study:

  • To investigate potential psychotic symptoms, specifically visual hallucinations, associated with naltrexone use in schizophrenia patients.
  • To raise clinical awareness regarding naltrexone's potential adverse effects in this vulnerable population.

Main Methods:

  • A case study approach was employed.
  • A relevant case report and literature review were conducted.

Main Results:

  • Findings suggest a potential association between naltrexone and the emergence of visual hallucinations.
  • This adverse effect may occur in patients with schizophrenia receiving naltrexone treatment.

Conclusions:

  • Naltrexone may be linked to visual hallucinations in schizophrenia patients.
  • Clinicians should exercise caution and monitor for these psychotic symptoms.
Keywords:
Drug-related side effects and adverse reactionsHallucinationsNaltrexoneNarcotic antagonists

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