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Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility
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Sexual dysfunction in men taking systemic dermatologic medication: A systematic review.

George A Zakhem1, Julia E Goldberg1, Catherine C Motosko1

  • 1Ronald O. Perelman Department of Dermatology, New York University School of Medicine, New York, New York.

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Summary

Systemic dermatologic medications can cause sexual dysfunction in men. This review identifies medications with sexual side effects and suggests screening protocols to help patients manage these issues.

Keywords:
anorgasmiaejaculation dysfunctionerectile dysfunctionimpotencelibidosexual dysfunctionsystemic medications

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Area of Science:

  • Dermatology
  • Pharmacology
  • Sexual Health

Background:

  • Prescription medications are a frequent cause of sexual dysfunction.
  • Patients often hesitate to report sexual side effects from medications.

Purpose of the Study:

  • To review evidence of sexual adverse effects in men using systemic dermatologic medications.
  • To propose screening protocols for identifying and managing these side effects.

Main Methods:

  • Systematic review of PubMed articles (inception to May 2018).
  • In-depth literature review of individual systemic dermatologic medications.
  • Inclusion criteria focused on studies evaluating sexual adverse effects.

Main Results:

  • 5,997 articles were initially reviewed; 59 articles on 11 medications met inclusion criteria.
  • Level 1 evidence for sexual adverse effects was found for finasteride.
  • Various systemic dermatologic medications were associated with sexual side effects.

Conclusions:

  • Many studies had limitations in sample size and methodology.
  • This review serves as a reference for adverse effects in therapeutic decisions.
  • It provides guidance for screening patients for sexual dysfunction.