Related Experiment Video

Updated: Jan 27, 2026

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies
15:48

ALS - Motor Neuron Disease: Mechanism and Development of New Therapies

Published on: July 29, 2007

10.0K

Frontotemporal Dementia with Motor Neuron Disease in a Patient with Antiphospholipid Syndrome: A Case Report

Yoon-Cheol Jeong1, Jin-Seok Park1, Seung-Hyun Kim1

  • 1Department of Neurology, Hanyang University College of Medicine, Seoul, Korea.

Dementia and Neurocognitive Disorders
|March 26, 2019
PubMed
Abstract

Insights

This rare case highlights frontotemporal dementia with motor neuron disease (FTD with MND) in a patient with antiphospholipid syndrome (APS). Further research into autoimmune factors in FTD with MND is warranted.

Area of Science:

  • Neurology
  • Immunology

Background:

  • Frontotemporal dementia with motor neuron disease (FTD with MND) is a progressive neurodegenerative syndrome with uncertain etiology.
  • FTD with MND involves neuronal loss in the frontal/temporal lobes and motor neurons, leading to behavioral, language, and muscle deficits.

Observation:

  • A 71-year-old male presented with a two-year history of progressive muscle weakness and cognitive decline.
  • Diagnostic workup included neurological examination, electromyography, brain imaging, and neuropsychological evaluation, confirming FTD with MND.
  • Antiphospholipid syndrome (APS) was identified, serving to exclude secondary causes of MND.

Findings:

  • The case presents a rare co-occurrence of FTD with MND and APS.
  • This association suggests a potential link between autoimmune processes and FTD with MND.

Implications:

  • Investigating the role of autoimmune pathogenesis in FTD with MND is crucial.
  • This case underscores the importance of considering autoimmune etiologies in complex neurodegenerative presentations.
Keywords:
antiphospholipid syndromefrontotemporal dementiamotor neuron disease

More Related Videos

Using Retinal Imaging to Study Dementia09:17

Using Retinal Imaging to Study Dementia

Published on: November 6, 2017

22.2K
Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica13:37

Extracellularly Identifying Motor Neurons for a Muscle Motor Pool in Aplysia californica

Published on: March 25, 2013

12.2K

Related Concept Videos

Dementia01:30

Dementia

Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
556
Data Reporting and Recording01:24

Data Reporting and Recording

Reporting and recording are crucial in data documentation. The timely, thorough, and accurate documentation of facts is essential when recording patient data. Failure to record findings during an assessment or interpretation of a problem will result in loss of information and make the patient document unreliable. The reader is left with general impressions if the information is not specific. A recording is documenting data of the individual's health information in a traceable, secure, and...
5.4K
Types of Reports I: Hands-off Report01:25

Types of Reports I: Hands-off Report

A hand-off report, also known as a change-of-shift report, is a crucial nursing process that ensures the smooth transition of patient care responsibilities between nursing staff.
Following are the key components and categories of hand-off reports:
Purpose and Process:
1.5K
Types of Reports II: Incident or Occurrence Report01:21

Types of Reports II: Incident or Occurrence Report

An Incident or Occurrence Report in a healthcare setting is a crucial document used to record any unexpected occurrence that may or may not have affected a patient, employee, or visitor. Such reports are critical to improving patient safety and include all details leading up to and including the event.
Purposes:
In the healthcare industry, reports play a crucial role in documenting incidents within an agency. The primary objective of these reports is to ensure patient safety, uphold the...
1.2K
Types of Reports III: Telephone and Verbal Reports01:26

Types of Reports III: Telephone and Verbal Reports

Telephone and Verbal Reports in healthcare settings are two communication methods for conveying therapeutic instructions from healthcare providers to nurses or other healthcare staff.
Here's an overview of each type:
Telephone Orders
1.0K
Motor Units00:46

Motor Units

A motor unit consists of two main components: a single efferent motor neuron (i.e., a neuron that carries impulses away from the central nervous system) and all of the muscle fibers it innervates. The motor neuron may innervate multiple muscle fibers, which are single cells, but only one motor neuron innervates a single muscle fiber.
61.8K