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Related Experiment Video

Updated: Jan 27, 2026

A Novel In Vitro Model of Blast Traumatic Brain Injury
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Blast injures to the thorax.

Zsolt Sziklavari1,2, Tamas F Molnar3,4

  • 1Department of Thoracic Surgery, Klinikum Coburg, Coburg, Germany.

Journal of Thoracic Disease
|March 26, 2019
PubMed
Summary

Blast lung injury, a severe consequence of explosive weapon use, lacks specific treatments. Current management focuses on supportive care and surgical intervention for secondary thoracic injuries.

Keywords:
Blast lung injurymilitary medicinethoracic trauma

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Area of Science:

  • Trauma Surgery
  • Pulmonary Medicine
  • Explosive Weaponry Effects

Background:

  • Explosive weapons frequently cause pulmonary blast injuries, affecting 10% of military casualties and 60-90% of civilian terror victims.
  • No targeted therapies exist for the primary lung shock-wave injury.
  • Existing treatments rely on mechanical ventilation, intensive care, and supportive measures.

Purpose of the Study:

  • To outline the management strategies for pulmonary blast injuries and associated thoracic trauma.
  • To emphasize the multidisciplinary approach required for optimal patient outcomes.

Main Methods:

  • Review of treatment protocols for primary blast lung injury.
  • Description of surgical management for secondary and tertiary blast thoracic injuries, including pleural space and hemorrhage control.
  • Discussion of parenchyma resection and delayed chest wall reconstruction.

Main Results:

  • Primary blast lung injury management is supportive, focusing on ventilation and intensive care.
  • Secondary and tertiary thoracic injuries necessitate damage control surgery, prioritizing pleural drainage and hemorrhage control.
  • Lung parenchyma resection is rarely required; non-anatomical resections are preferred when necessary.

Conclusions:

  • Blast lung injury management is primarily supportive, with surgical intervention reserved for secondary and tertiary thoracic damage.
  • A multidisciplinary approach is crucial for managing blast-related chest trauma.
  • Patient outcomes are significantly impacted by the presence of concomitant injuries.