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Considerations and quality controls when analyzing cell-free tumor DNA.

Gustav Johansson1,2,3, Daniel Andersson1, Stefan Filges1

  • 1Sahlgrenska Cancer Center, Department of Pathology and Genetics, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Medicinaregatan 1F, 413 90, Gothenburg, Sweden.

Biomolecular Detection and Quantification
|March 26, 2019
PubMed
Summary

Optimizing the liquid biopsy workflow is crucial for reliable circulating tumor DNA (ctDNA) detection. Quantitative PCR assays ensure robust ctDNA analysis for improved cancer diagnostics.

Keywords:
Cell-free DNACell-free tumor DNADNA barcodingLiquid biopsyMutation detectionPlasmaQuality controlsSample preprocessingSiMSen-Seq

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