Matrix metalloproteinase 13, a new target for therapy in Alzheimer's disease

PrPC limits APP delivery to the plasma membrane and alters its processing to facilitate Aβ release.

Neurobiology of disease·2026

Native PLGA nanoparticles attenuate disease pathology via multiple pathways in 5xFAD Alzheimer's model.

Alzheimer's & dementia : the journal of the Alzheimer's Association·2026

mRNA m6A modifications and the RNA-binding protein YTHDF1 affect translational control in both normal and pathological learning.

Proceedings of the National Academy of Sciences of the United States of America·2026

Female-specific Cx3cr1-driven regulation of ALS and Alzheimer's risk genes in tauopathy.

Molecular neurodegeneration advances·2026

Spatiotemporal transcriptomic profiling reveals upregulation of glycolysis pathway genes before overt tauopathy in the PS19 mouse model.

Experimental & molecular medicine·2026

PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia.

Nature·2025

LAMA5 pathogenic variant uncovers a novel autoantigen in membranous nephropathy.

Genes & diseases·2026

PINK1 deficiency exacerbates age-related bone loss in association with enhanced inflammatory adipocyte differentiation.

Genes & diseases·2026

Single-cell sequencing-guided discovery of narciclasine as a dual VCAM-1/ICAM-1 inhibitor for atherosclerosis management.

Genes & diseases·2026

Autosomal dominant gain-of-function mutations in LCP1 cause a syndromic neutropenia and immunodeficiency.

Genes & diseases·2026

High-throughput chemical screen identifies epothilone B in modulating inflammatory bowel disease by triggering neutrophil apoptosis.

Genes & diseases·2026

ZO-2 blocks the localization of PGAM5 protein to the mitochondrial membrane and suppresses pancreatic cancer malignancy through metabolic reprogramming.

Genes & diseases·2026

Effect of Maranta arundinacea L. ethanolic extract against chronic inflammation in CFA-induced arthritis rats.

Journal of complementary & integrative medicine·2026

Ultrasound-Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

Label-free ultraviolet photoacoustic microscopy for multiscale structural phenotyping of epithelial morphogenesis in organoid-derived intestinal epithelial wrinkle tissue.

Photoacoustics·2026

Transcriptomic trajectory of hepatocyte ballooning reveals a lipotoxic point of no return and initiates oncogenic regulatory rewiring in MASLD.

Biochemistry and biophysics reports·2026

Neutrophil-mediated BDNF delivery for the treatment of moderate to severe Alzheimer's disease.

Acta pharmaceutica Sinica. B·2026

Related Experiment Videos

Matrix metalloproteinase 13, a new target for therapy in Alzheimer's disease

Related Concept Videos

PrPC limits APP delivery to the plasma membrane and alters its processing to facilitate Aβ release.

Native PLGA nanoparticles attenuate disease pathology via multiple pathways in 5xFAD Alzheimer's model.

mRNA m6A modifications and the RNA-binding protein YTHDF1 affect translational control in both normal and pathological learning.

Female-specific Cx3cr1-driven regulation of ALS and Alzheimer's risk genes in tauopathy.

Spatiotemporal transcriptomic profiling reveals upregulation of glycolysis pathway genes before overt tauopathy in the PS19 mouse model.

PICALM Alzheimer's risk allele causes aberrant lipid droplets in microglia.

LAMA5 pathogenic variant uncovers a novel autoantigen in membranous nephropathy.

PINK1 deficiency exacerbates age-related bone loss in association with enhanced inflammatory adipocyte differentiation.

Single-cell sequencing-guided discovery of narciclasine as a dual VCAM-1/ICAM-1 inhibitor for atherosclerosis management.

Autosomal dominant gain-of-function mutations in LCP1 cause a syndromic neutropenia and immunodeficiency.

High-throughput chemical screen identifies epothilone B in modulating inflammatory bowel disease by triggering neutrophil apoptosis.

ZO-2 blocks the localization of PGAM5 protein to the mitochondrial membrane and suppresses pancreatic cancer malignancy through metabolic reprogramming.

Effect of Maranta arundinacea L. ethanolic extract against chronic inflammation in CFA-induced arthritis rats.

Ultrasound-Responsive Piezoelectric Fibrous Membrane Promotes Neurological Recovery After TBI by Modulating Microglial Polarization via Restoring Mitochondrial Dynamic Homeostasis.

Label-free ultraviolet photoacoustic microscopy for multiscale structural phenotyping of epithelial morphogenesis in organoid-derived intestinal epithelial wrinkle tissue.

Transcriptomic trajectory of hepatocyte ballooning reveals a lipotoxic point of no return and initiates oncogenic regulatory rewiring in MASLD.

Neutrophil-mediated BDNF delivery for the treatment of moderate to severe Alzheimer's disease.

Related Experiment Videos

Matrix metalloproteinase 13, a new target for therapy in Alzheimer's disease

Related Concept Videos

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