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Updated: Jan 27, 2026
05:39
Dermoscopy Aids in the Diagnosis of Discoid Lupus Erythematosus
Published on: May 16, 2025
597
Left ventricular pseudoaneurysm associated with systemic lupus erythematosus.
L S Hoff1, C Q Pimentel1, B L R Faillace2
11 Division of Rheumatology, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, São Paulo, Brazil.
Lupus
|March 26, 2019
Summary
Systemic lupus erythematosus (SLE) can cause rare cardiac issues like left ventricular pseudoaneurysms. This case highlights a potential autoimmune link in SLE patients with heart failure.
Area of Science:
- Cardiology
- Rheumatology
- Pathology
Background:
- Systemic lupus erythematosus (SLE) is linked to various cardiac problems.
- Left ventricular (LV) pseudoaneurysms are not previously reported in SLE.
- Cardiac complications in SLE require further investigation.
Observation:
- A 30-year-old woman with a diagnosed flare of SLE presented with heart failure symptoms.
- Diagnostic imaging revealed a large left ventricular pseudoaneurysm.
- Other potential causes including trauma, prior surgery, and antiphospholipid syndrome were excluded.
Findings:
- The patient underwent successful surgical repair of the left ventricular pseudoaneurysm using a pericardial patch.
- Histopathological examination of the pericardium showed lymphocytic arteriolitis.
- Coronary arteries were normal, and cardiac MRI showed no myocardial fibrosis or infarction.
Implications:
- This case suggests a potential autoimmune-mediated mechanism for left ventricular pseudoaneurysm in SLE.
- The findings highlight the importance of considering rare cardiac complications in lupus patients.
- Further research may elucidate the role of autoimmune arteriolitis in SLE-associated cardiac pathology.
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