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Making MR Imaging Child's Play - Pediatric Neuroimaging Protocol, Guidelines and Procedure

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A protocol for developing reporting guidelines for laboratory studies in Endodontology.

V Nagendrababu¹, P E Murray², R Ordinola-Zapata³

¹Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.

International Endodontic Journal

|March 26, 2019

Summary

This summary is machine-generated.

New guidelines called Preferred Reporting Items for Laboratory studies in Endodontology (PRILE) will improve the quality of endodontology research. These guidelines aim to reduce manuscript rejections and enhance the reliability of laboratory studies in the field.

Keywords:

endodontics endodontology laboratory studies quality reporting guidelines

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Area of Science:

Endodontology
Biomedical Research
Scientific Publishing

Background:

Laboratory-based research is prevalent in Endodontology, contributing valuable data for clinical practice.
Many submitted laboratory studies face rejection or require significant revisions due to methodological flaws.
A lack of systematic approaches for evaluating laboratory study quality affects authors and reviewers.

Purpose of the Study:

To establish and publish quality guidelines for reporting laboratory studies in Endodontology.
To introduce the Preferred Reporting Items for Laboratory studies in Endodontology (PRILE) guidelines.
To aid authors in avoiding manuscript rejection and assist editors/reviewers in systematic evaluation.

Main Methods:

A five-phase consensus process involving a steering committee, PRILE Delphi Group (PDG), and PRILE Face-to-Face Consensus Meeting Group (PFCMG).
Identification and adaptation of existing guideline items, with refinement through Likert scale evaluations and group discussions.
Development of draft guidelines, subject to final approval by the steering committee.

Main Results:

The development of the PRILE guidelines through a rigorous consensus process.
The guidelines are designed to address common flaws and limitations in laboratory-based endodontology research.
A systematic approach for evaluating and reporting laboratory studies will be established.

Conclusions:

The PRILE guidelines will enhance the quality and reliability of Endodontology research.
Implementation of PRILE is expected to reduce manuscript rejection rates and improve scientific rigor.
Dissemination through publications, presentations, and a dedicated website will ensure broad accessibility and adoption.