Related Experiment Video
Updated: Jan 27, 2026
09:42
Author Spotlight: Using Motor Imagery Brain-Computer Interface to Improve Motor and Cognitive Function in Stroke Patients
Published on: September 1, 2023
2.1K
Gait Dysfunction in Motoric Cognitive Risk Syndrome
Emmeline Ayers1, Joe Verghese1,2
1Department of Neurology, Albert Einstein College of Medicine, Bronx, NY, USA.
Journal of Alzheimer'S Disease : JAD
|March 26, 2019
Summary
Motoric cognitive risk (MCR) syndrome is common in older adults and linked to dementia risk. Gait abnormalities in MCR are frequent and predict worsening disability, but not cognitive decline.
Area of Science:
- Gerontology
- Neurology
- Public Health
Background:
- Motoric cognitive risk (MCR) syndrome is a condition affecting older adults, characterized by cognitive and motor impairments.
- MCR is associated with an increased risk of developing dementia.
- The specific clinical features of MCR, particularly gait abnormalities, require further elucidation.
Purpose of the Study:
- To systematically investigate the prevalence and types of clinical gait abnormalities in older adults diagnosed with MCR.
- To explore the relationship between gait abnormalities in MCR and subsequent cognitive and functional decline.
Main Methods:
- The study analyzed data from 522 community-dwelling older adults (aged 65+).
- Participants were assessed for MCR, including subtypes based on gait velocity and variability.
- Clinical gait abnormalities (neurological and non-neurological) were identified, and their association with decline over a median 3.02-year follow-up was examined.
Main Results:
- Gait abnormalities were prevalent across all MCR subtypes, ranging from 44% to 61%.
- Both neurological and non-neurological gait issues were common, with specific subtypes showing higher frequencies.
- The presence of gait abnormalities at baseline predicted increased disability scores during follow-up.
Conclusions:
- Clinical gait abnormalities are a common feature of MCR syndrome and its various subtypes.
- These gait abnormalities are significantly associated with accelerated functional decline in individuals with MCR.
Related Concept Videos
01:38Cognitive Dissonance
36.8K
Social psychologists have documented that feeling good about ourselves and maintaining positive self-esteem is a powerful motivator of human behavior (Tavris & Aronson, 2008). In the United States, members of the predominant culture typically think very highly of themselves and view themselves as good people who are above average on many desirable traits (Ehrlinger, Gilovich, & Ross, 2005). Often, our behavior, attitudes, and beliefs are affected when we experience a threat to our...
36.8K
01:12Relative Risk
2.1K
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
2.1K
01:26Factors Affecting the Risk of Infection
13.3K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
13.3K
01:27Language and Cognition
754
Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
754
01:25Cognitive Therapy
959
Cognitive therapy, pioneered by Aaron T. Beck in the 1960s, is a structured approach to addressing psychological distress by focusing on the influence of thoughts on emotions and behaviors. All cognitive therapies involve the basic assumption that human beings have control over their feelings, and that how individuals feel about something depends on how they think about it. Unlike psychoanalytic methods that delve into unconscious processes or humanistic approaches emphasizing...
959
01:23Cognition and Behavior
314
Social psychology examines the complex interplay between individual mental processes and social interactions. Historically, the field was divided into two domains: social behavior and social cognition. Researchers focusing on social behavior analyzed actions within social contexts, such as conformity, aggression, or cooperation. Meanwhile, social cognition researchers investigated how people perceive, interpret, and mentally represent their social environments. However, modern perspectives no...
314