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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
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Peptide Bonds02:43

Peptide Bonds

A peptide bond covalently attaches amino acids through a dehydration reaction. One amino acid's carboxyl group and another amino acid's amino group combine, releasing a water molecule. The resulting bond is the peptide bond. The products that such linkages form are peptides. As more amino acids join this growing chain, the resulting chain is a polypeptide. Each polypeptide has a free amino group at one end. This end has the N-terminal, or the amino-terminal, and the other end has a free...
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Power System Three-Phase Short Circuits01:21

Power System Three-Phase Short Circuits

Determining the subtransient fault current in a power system involves representing transformers by their leakage reactances, transmission lines by their equivalent series reactances, and synchronous machines as constant voltage sources behind their subtransient reactances. In this analysis, certain elements are excluded, such as winding resistances, series resistances, shunt admittances, delta-Y phase shifts, armature resistance, saturation, saliency, non-rotating impedance loads, and small...
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Short-distance Transport of Resources02:12

Short-distance Transport of Resources

Short-distance transport refers to transport that occurs over a distance of just 2-3 cells, crossing the plasma membrane in the process. Small uncharged molecules, such as oxygen, carbon dioxide, and water, can diffuse across the plasma membrane on their own. In contrast, ions and larger molecules require the assistance of transport proteins due to their charge or size. Transport across membranes also occurs within individual cells, playing a variety of essential roles for the plant as a whole.
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Three-Phase Short Circuit—Unloaded Synchronous Machine01:21

Three-Phase Short Circuit—Unloaded Synchronous Machine

Conducting a three-phase short circuit test on an unloaded synchronous machine helps understand its impact on the system. The AC fault current's oscillogram, with the DC offset removed, reveals that the waveform amplitude decreases from an initially high value to a steady-state level for one phase of the machine.
This behavior occurs due to the magnetic flux produced by the short-circuit armature currents. Initially, these currents follow high-reluctance paths but eventually shift to...
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Peptide Identification Using Tandem Mass Spectrometry01:33

Peptide Identification Using Tandem Mass Spectrometry

Tandem mass spectrometry, also known as MS/MS or MS2, is an analytical technique that employs two mass analyzers. Essentially it is a series of mass spectrometers that helps isolate a particular biomolecule and then helps study its chemical properties.
This technique helps gather information regarding the protein from which the peptide was obtained and to study the peptides’ amino acid sequence. Identifying peptides from a complex mixture is an important component of the growing field of...
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