Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gas Exchange and Transport01:20

Gas Exchange and Transport

76.7K
Gas exchange, the intake of molecular oxygen (O2) from the environment and the outflow of carbon dioxide (CO2) into the environment, is necessary for cellular function. Gas exchange during respiration occurs largely via the movement of gas molecules along pressure gradients. Gas travels from areas of higher partial pressure to areas of lower partial pressure. In mammals, gas exchange occurs in the alveoli of the lungs, which are adjacent to capillaries and share a membrane with them.
76.7K
Social Exchange Theory02:06

Social Exchange Theory

39.5K
We have discussed why we form relationships, what attracts us to others, and different types of love. But what determines whether we are satisfied with and stay in a relationship? One theory that provides an explanation is social exchange theory. According to social exchange theory, we act as naïve economists in keeping a tally of the ratio of costs and benefits of forming and maintaining a relationship with others (Rusbult & Van Lange, 2003).
39.5K
Social Exchange Theory01:26

Social Exchange Theory

456
As formulated by John Thibaut and Harold Kelley, Social Exchange Theory explains human relationships as economic-like exchanges that maximize rewards and minimize costs. This theory suggests that individuals engage in relationships to gain benefits and reduce burdens, similar to economic transactions. It has been widely applied to various types of relationships, including romantic, professional, and social interactions.Rewards and Costs in RelationshipsRelationship rewards include emotional...
456
Capillary Exchange01:28

Capillary Exchange

10.9K
The cardiovascular system's chief role is to disseminate gases, nutrients, waste, and other substances to the body's cells. Small molecules like gases, lipids, and lipid-soluble substances directly diffuse through capillary wall endothelial cell membranes. Glucose, amino acids, and ions, including sodium, potassium, calcium, and chloride, use transporters for facilitated diffusion via membrane-specific channels. Glucose, ions, and bigger molecules may also pass through intercellular...
10.9K
Red Algae01:23

Red Algae

803
Red algae, also known as rhodophytes, are primarily found in marine environments, though some species inhabit freshwater and terrestrial ecosystems. These organisms exist in both unicellular and multicellular forms, with some multicellular varieties reaching macroscopic sizes.As phototrophic organisms, red algae contain chlorophyll a; however, their chloroplasts lack chlorophyll b. Instead, they possess phycobiliproteins, which serve as major light-harvesting pigments, similar to those found in...
803
Ion Exchange01:17

Ion Exchange

1.2K
Ion exchange chromatography separates charged molecules from a solution by reversibly exchanging them with mobile, or 'active', ions associated with the oppositely charged stationary phase. This method can be used to separate ions, soften and deionize water, and purify solutions. The polymers comprising the ion-exchange column are high-molecular-weight and chemically stable polymers, crosslinked to be porous and essentially insoluble. They are also functionalized with either acidic or...
1.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simple method to predict lymphocyte collection for chimeric antigen receptor T-cell engineering.

Transfusion clinique et biologique : journal de la Societe francaise de transfusion sanguine·2025
Same author

Position paper on advancing sickle cell disease management in France by bridging the clinical practices and guidelines through expert insights.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2024
Same author

Red blood cell exchange in an emergency in sickle cell disease.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2020
Same author

Red blood cell exchange in children and adolescents with sickle cell disease.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2019
Same author

Automatic depletion with Spectra Optia allows a safe 16% reduction of red blood cell pack consumption in exchanged sickle cell anemia patients.

Transfusion·2019
Same author

Decompressive craniectomy in the treatment of post-traumatic intracranial hypertension in children: our philosophy and indications.

Journal of neurosurgical sciences·2015
Same journal

Therapeutic plasma exchange and immunomodulatory strategies in post-infectious syndromes: A review of immune dysregulation in PTLDS, long COVID, ME/CFS, and PANS/PANDAS.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

Therapeutic plasma exchange in Alzheimer's disease: From clinical trial to real-world evidence.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

Successful treatment of pure red cell aplasia with Orelabrutinib following major ABO-incompatible hematopoietic stem cell transplantation for acute myeloid leukemia: A case report.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

Technological advances in selective plasma adsorption: The MTx.100 column and the emergence of subtractive precision medicine.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

What's happening? Editorial comment: Insights on artificial intelligence, cell therapy and stem cell transplantation safety.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
Same journal

Red blood cell transfusion in elderly patients: Hemoglobin thresholds and clinical outcomes.

Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis·2026
See all related articles

Related Experiment Video

Updated: Jan 27, 2026

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
09:12

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

Published on: January 12, 2018

15.4K

Red blood cell exchange techniques and methods.

F Driss1, O Hequet2

  • 1Service d'hématologie biologique, Centre Hospitalier universitaire Bicêtre, le Kremlin-Bicêtre, France.

Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis
|March 27, 2019
PubMed
Summary
This summary is machine-generated.

Red blood cell exchange (RBCX) is a key therapy for sickle cell disease (SCD), effectively removing abnormal red blood cells. Advances in RBCX techniques allow for precise removal and targeted treatment, optimizing patient care.

Keywords:
Red blood cell exchangeSickle cell disease

More Related Videos

A Simple Red Blood Cell Lysis Method for the Establishment of B Lymphoblastoid Cell Lines
09:49

A Simple Red Blood Cell Lysis Method for the Establishment of B Lymphoblastoid Cell Lines

Published on: January 14, 2017

15.4K
Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
06:29

Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells

Published on: January 29, 2014

31.1K

Related Experiment Videos

Last Updated: Jan 27, 2026

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry
09:12

Measuring Deformability and Red Cell Heterogeneity in Blood by Ektacytometry

Published on: January 12, 2018

15.4K
A Simple Red Blood Cell Lysis Method for the Establishment of B Lymphoblastoid Cell Lines
09:49

A Simple Red Blood Cell Lysis Method for the Establishment of B Lymphoblastoid Cell Lines

Published on: January 14, 2017

15.4K
Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells
06:29

Methods for Quantitative Detection of Antibody-induced Complement Activation on Red Blood Cells

Published on: January 29, 2014

31.1K

Area of Science:

  • Hematology
  • Transfusion Medicine
  • Sickle Cell Disease Management

Background:

  • Red blood cell exchange (RBCX) is a standard treatment for sickle cell disease (SCD).
  • RBCX aims to remove abnormal sickle red blood cells (RBCs).
  • Therapeutic techniques for RBCX have evolved significantly over recent decades.

Purpose of the Study:

  • To review current RBCX techniques, methods, and targets for SCD.
  • To summarize optimal schedules for RBCX procedures.
  • To identify areas requiring further research in RBCX therapy.

Main Methods:

  • Literature review of RBCX techniques and outcomes in SCD.
  • Analysis of advancements in precision and target setting for RBCX.
  • Synthesis of clinical and biological data related to RBCX efficacy.

Main Results:

  • RBCX techniques have improved, enabling more precise removal of sickle RBCs.
  • Specific hematological targets can now be set and achieved with RBCX.
  • Optimized procedures result from enhanced knowledge of techniques and targets.

Conclusions:

  • RBCX is an evolving and effective therapy for managing SCD.
  • Further investigation is needed to address outstanding issues in RBCX.
  • Continued research will refine RBCX protocols for better patient outcomes.